Study On Medical Plasma Pathogen Inactivation System

In the medical system,in order to further improve and ensure the safety of plasma,it is necessary to inactivate plasma at low temperature on the basis of blood screening.At present,the inactivation treatment in foreign countries has low efficiency and large workload,and can only achieve manual operation and single chamber treatment of blood bags,and manual operation is easy to cause pollution to plasma quality.The research in related fields in China has not yet made great achievements.To solve these problems,the medical plasma pathogen inactivation system studied in this paper adopts fuzzy PID control algorithm and compressor refrigeration technology for constant temperature control,which realizes intelligent automatic control of multi-cabin.It not only solved the temperature problem of inactivation treatment environment,but also achieved high efficiency and high quality automatic inactivation of medical pathogens at low temperature.It met the requirements of blood center and medical institution for clinical transfusion and cryopreservation of bagged plasma.Firstly,the plasma pathogen inactivation system was studied in this paper,the internal working mechanism of the inactivation system was analyzed.During the inactivation treatment,the blood bags in the third compartment were inactivated at the same time,and 36 ultraviolet lamp tubes released a lot of heat.Therefore,in the closed space of the deactivation cabinet,there are some problems,such as rapid heat accumulation,limited heat dissipation capacity and uneven temperature distribution.Secondly,according to these temperature variation characteristics,the temperature control method was studied,and the composite control algorithm combining fuzzy control and PID control was established.On the basis of the conventional PID controller,the temperature deviation and rate of change were continuously detected,and the tuning function of proportional,integral and differential parameters of the PID controller was realized according to the fuzzy logic rule and the rule inference to meet the requirements of the temperature deviation and rate of change at any time.The algorithm realizes low temperature control in the closed cabin,and the system response is fast and accurate.In addition,the inactivation control system based on PLC was developed in this paper,which realized the modular design of the system.Including the inactivation treatment cabinet,which realized the function of avoiding light and heat;the design of the low frequency vibration device,which realized the function of 1 Hz horizontal low amplitude oscillation of blood bag,so that the blood bag was uniformly irradiated by ultraviolet rays;the design of the inactivation processing chamber,which realized the up-and-down displacement adjustment function of the lamp holder and the function of automatically entering and leaving the cabin;the design of the temperature refrigeration module,which realized functions such as temperature measurement,alarm and low temperature control.the design of the interactive interface of the upper computer,which realized a simple and fast operating system.Finally,the practical application shows that the medical plasma pathogen inactivation system is simple to maintain,convenient to replace,safe and reliable which ensures that the temperature of plasma in the inactivation cabinet is always controlled in the range of 4(±2)℃.It realizes the integration and automation of three blood bags for inactivation at the same time,and meets the basic requirements of medical units for plasma pathogen inactivation.