Study On The Association Between Meteorological Factors,Air Pollution And Cerebrovascular Accidents In Rural Areas Of Qingyang

Objective:To investigate the association between temperature,air pollution indicators and cerebrovascular accident admissions in rural areas,and to analyze the delayed effect of various factors on cerebrovascular accidents,and provide reference for the prevention and treatment of cerebrovascular accidents in rural areas of Qingyang.Methods:Data on cerebrovascular accident admissions,meteorological and air pollution indicators were collected in rural areas of Qingyang.Based on the admissions data of cerebrovascular accidents in rural areas from 2010 to 2016,combined with meteorological data,a mixed generalized additive model was constructed based on the GAM to explore the correlation between temperature indicators and cerebrovascular accidents and its hysteresis effect.Using the data of air pollution and cerebrovascular accident admissions,2015-2016,the distribution lag nonlinear model was used to explore the effects of PM_2.5,PM₁₀,SO₂ and other air pollution indicators on cerebrovascular accidents.Results:1.The average temperature had the greatest impact on ischemic cerebrovascular accident in males aged 65 and over,with an excess risk of 1.867%.The maximum temperature was more pronounced for males aged 65 and older,with a relative risk of 1.018.The 24h temperature change had the greatest impact on males aged 65years and older,and diurnal temperature range was only statistically significant in males over 65 years of age?p<0.05?.The average temperature,maximum temperature and minimum temperature had statistically significant effects on female hemorrhagic cerebrovascular accident?p<0.05?.With the increase of the average temperature,the effect on the ischemic cerebrovascular accident in each subgroup was firstly increased,reaching a maximum at around 20?,then decreasing,and the impact on hemorrhagic cerebrovascular accidents was generally declining.2.The optimal single-lag effect and moving average cumulative lag effect of temperature indicators on the ischemic cerebrovascular accident for aged?65 were statistically significant.In addition to the cumulative lag effect of the maximum temperature and the single lag effect of the 24h temperature change,the delayed effect of other indicators were statistically significant for<65 males.Other indicators,except the maximum temperature,had a statistically significant lag effect on ischemic cerebrovascular accident in women<65 years of age.3.The effects of SO₂ and CO on ischemic cerebrovascular accident were statistically significant in the three subgroups of<65-year-old males,?65-year-old females,and females under 65 years of age?p<0.05?.SO₂ had the greatest impact on female population under 65 years old,and its relative risk was 1.427.CO had the greatest impact on males under 65 years of age,with a relative risk equal to 1.318.The effect of PM_2.5 on male hemorrhagic cerebrovascular accident in rural areas of Qingyang was also statistically significant?p<0.05?.4.The impact of PM_2.5 on the ischemic cerebrovascular accident in each subgroup had obvious hysteresis effect,and the lag effect was most maximized on the 14th day.The impact of PM₁₀ on ischemic cerebrovascular accident in males under 65 years of age had the greatest effect on the day,and the short-term lag effect was obvious.There was no significant difference in the hysteresis effect of PM₁₀ on cerebrovascular accidents in other subgroups?p>0.05?.5.The effect of SO₂ on the ischemic cerebrovascular accident in each subgroup had different degrees of hysteresis,but the hysteresis effect of SO₂ on hemorrhagic cerebrovascular accident was not statistically significant.The impact of CO on the ischemic cerebrovascular accident in each subgroup had a mid-and long-term lag effect.There was short-term lag effect of NO₂ on the ischemic cerebrovascular accident in some subgroups.The delayed effect of O₃ on the ischemic cerebrovascular accident in each subgroup was also not statistically significant.Conclusion:1.The temperature indicators had an effect on the ischemic cerebrovascular accident in each subgroup of Qingyang rural areas,and the effect of temperature indicators on the subgroup aged 65 and over was generally higher than<65 year old.The temperature index had an effect on female hemorrhagic cerebrovascular accidents in rural areas of Qingyang,but had no lag effect on males.2.There were hysteresis effects of the temperature indicators on the ischemic cerebrovascular accident.The delayed effect of temperature indicators in people aged 65 and over was more pronounced for men.There was a hysteresis effect on the impact of temperature indicators on female hemorrhagic cerebrovascular accident,while the male lag effect was not obvious.3.There was a nonlinear correlation between the concentration of particulate matter and the counts of cerebrovascular accidents.The impact of PM_2.5 on the ischemic cerebrovascular accident in each subgroup had obvious hysteresis effect,and the effect reached the maximum on the 14th day.PM_2.5 also had delayed effect on the hemorrhagic cerebrovascular accident in men.PM₁₀ had only short-term lag effect on ischemic cerebrovascular accident in males younger than 65 years of age.4.The impact of SO₂ on the ischemic cerebrovascular accident in each subgroup had different degrees of hysteresis,and the cumulative effect on female population under 65 years old was the largest.The cumulative effect of CO on ischemic cerebrovascular accidents in males under 65 years of age was greatest.There was a short-term delayed effect of NO₂ on the ischemic cerebrovascular accident in some subgroups.