| OBJECTIVE:By investigating the intrinsic relationship between fundus changes and systemic hemorheology related factors in patients with hypertension retinal arteriosclerosis,the relationship between fundus blood vessels and heart and cerebrovascular diseases was found,thus providing a basis for inferring systemic disease through fundus vascular changes.METHOD:A retrospective analysis of the patients who were diagnosed with ophthalmology at the China-Japan Hospital between October 2016 and October 2017 revealed a total of 320 patients with retinal arteriosclerosis and hypertension.The ophthalmologic examination was performed on the patients:including central vision(naked eye).Visual acuity,corrected visual acuity,intraocular pressure,slit lamp examination,necessary dilated pupil examination of fundus.In order to ensure the objectivity of the examination results,the examination was completed and recorded by a doctor.A detailed questionnaire survey was conducted on the subjects to be included.The survey included age,gender,height(H),weight(W),past medical history,and especially dyslipidemia,and collected nearly three months of color Doppler ultrasonography of cervical vessels.Check,biochemical and blood test results in the last month.To calculate the percentage of retinal arteriosclerosis at grade Ⅰ,grade Ⅱ,and grade Ⅲ in retinal arteriosclerosis with different diseases,with different abnormal blood rheology parameters,and different degrees of obesity,and to compare the proportion of retinal arteriosclerosis at each level.RESULT:(1)Grade Ⅲ retinal arteriosclerosis is only present in patients with hypertension with retinal arteriosclerosis and dyslipidemia.(2)The longer the duration of dyslipidemia,the greater the proportion of retinal arteriosclerosis in grades Ⅱ and Ⅲ.(3)Arteriosclerosis of grade Ⅱ is the largest proportion of arteriosclerosis at all levels in hypertensive retinal atherosclerosis patients with diabetes.(4)In patients with hypertension and retinal arteriosclerosis,obese patients have the largest proportion of grade Ⅱarteriosclerosis,and the normal body type patients have the largest proportion of grade Ⅰ.(5)In patients with hypertensive retinal arteriosclerosis with diabetes and overweight or obesity,the proportion of grade Ⅱ and Ⅲ retinal arteriosclerosis increased,and the grade Ⅱ was the main factor.(6)In patients with hypertensive retinal arteriosclerosis with abnormal glucose and dyslipidemia and being overweight or obese,the proportion of grade Ⅱ and Ⅲ retinal arteriosclerosis increased,and was mainly grade Ⅱ.(7)In hypertensive retinal arteriosclerosis patients with abnormal glucose and dyslipidemia and being overweight or obese,the longer the duration of dyslipidemia,the greater the proportion of grade Ⅲ retinal arteriosclerosis.(8)The proportion of grade Ⅲ retinal arteriosclerosis was significantly increased in hypertensive retinal arteriosclerosis with dyslipidemia,diabetes,and overweight or obesity.(9)Hypertensive retinal arteriosclerosis patients with mixed hyperlipidemia had the largest proportion of retinal arteriosclerosis at grade Ⅲ.(10)When the level of LDL-C increases,the proportion of retinal arteriosclerosis is greater in grade Ⅲ,and the proportion of retinal arteriosclerosis in grade Ⅱ is the largest among patients with elevated Lp(a).(11)Grade Ⅱretinal arteriosclerosis accounted for the largest proportion of patients with abnormal HCT,and grade Ⅲ retinal arteriosclerosis accounted for the largest proportion of patients with abnormal PLT.CONCLUSION:(1)Hypertension Retinal arteriosclerosis is associated with dyslipidemia,diabetes,obesity and overweight,and hemorheological factors.When atherosclerosis is aggravated,attention should be paid to the presence of cardiovascular and cerebrovascular diseases.(2)As the medical history increases,the course of dyslipidemia increases,especially BMI increases the severity of retinal arteriosclerosis.(3)TC and TG increased simultaneously,HCY increased,LDL-C increased,Lp(a)increased,HCT abnormality,and abnormal PLT were sensitive indicators of the degree of retinal arteriosclerosis in hypertension.Part Ⅱ:Study on the related factors of between the TCM Syndrome of Central Retinal Artery Occlusion and Cardiovascular DiseasesOBJECTIVE:To find the relationship between TCM syndrome types and cardiovascular and cerebrovascular diseases in central retinal artery occlusion by exploring the related factors of between the TCM Syndrome of Central Retinal Artery Occlusion and Cardiovascular Diseases to Provides feasible advice for clinical prevention of central retinal artery occlusion.METHOD:A total of 32 patients(32 eyes)with central retinal artery occlusion diagnosed at the China-Japan Friendship Hospital from October 2016 to October 2017 were examined.The patients were subjected to eye examinations including central vision(uncorrected visual acuity,corrected visual acuity),and eyes.Pressure,slit lamp examination,direct ophthalmoscope fundus examination,dilated eye examination fundus,fundus fluorescein angiography.In order to ensure the objectivity of the examination results,the examination was completed and recorded by a doctor.At the same time,a detailed questionnaire survey was conducted on the subjects included in the survey,including the age,gender,height,weight,and past medical history.Calculate the percentage of TCM syndromes in central artery obstruction with different diseases and compare the proportion of each syndrome.RESULT:The history of hypertensive patients with central retinal artery occlusion in liver yang syndrome is more common.The qi stagnation and blood stasis syndrome with central retinal artery occlusion in patients with a history of coronary heart disease is more common.Qi deficiency and blood stasis syndrome central retinal artery occlusion patients with a history of cerebral infarction is more common.CONCLUSION:(1)Occurrence of central retinal artery occlusion is associated with hypertension,dyslipidemia,coronary heart disease,and cerebral infarction.(2)Patients with high age,complex medical history and dialectical hyperactivity of liver-yang syndrome,coronary heart disease patients with qi stagnation and blood stasis syndrome,and cerebral infarction patients with qi deficiency and blood stasis syndrome should be alert to the occurrence of central retinal artery occlusion. |
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