| ObjectiveThis dissertation aims to develop the clinical experience of a famous Traditional Chinese Medicine(TCM)practitioner as well as to provide as references for other practitioners.MethodsThis dissertation summarizes professor Feng Xinghua’s academic experiences in treating primary sjogren syndrome(PSS)with thrombocytopenia by clinical learning,collecting medical records,consulting books and searching literatures.To summarize and analyze the recent study progress of sjogren syndrome with thrombocytopenia and TCM understand and treatment of thrombocytopenia by means of reading ancient books and searching literatures online.Results1.The pathogenesis of sjogren syndrome with thrombocytopenia is not clear and there is no standardized treatment.The present treatment mostly consults the directory of Systemic Lupus Erythematosus(SLE)or Inmmune Thrombocytopenia(ITP)by apply hormone,IVIG,immunosuppressant,blood transfusion.These therapies have severe compliments and some patients may be insensitive to hormone or relapse easily with a long history,which brings huge difficulties to cure.According to clinical manifestations,Professor Feng treats it via"xue syndrome",and"xu-lao syndrome" theory.2.Professor Feng"s understanding in etiology and pathogenesis:professor Feng put forward the academic thought that Qi and yin deficiency is the root and excessive dryness-heat is the branch.He holds the opinions that PSS is very common in middle aged women who regard the blood as basis and the liver yin and liver blood are usually not enough,as well as Tiangui is increasingly insufficient after 40 years old which decides their constitution of yin and blood deficiency,and easily to attacked by excessive dry-heat pathogens,which finally leads to qi and yin deficiency.Qi and yin deficiency is important for disease occurrence:Deficient qi can’t produce and regulate the fluid.The yin and fluid deficiency transforms to dryness which causes the organs lack nourishment;Qi and yin deficiency triggers bleeding.Deficient qi can’t regulate blood and yin deficiency produces deficient fire internally,which lead to bleed.Meanwhile,Qi and yin deficiency is the result of bleeding.When the blood is lost,qi loses its attachment and the body fluid loses its source,which further worsens the degree of qi and yin deficiency.Excessive dryness-heat is the disease’s substantial pathological factor.Excessive dryness-heat burns body fluid and consumes qi and blood,causes the pathological changes of "aridity produced by excessive dryness" and "excessive heat brings about bleeding."3.Professor Feng’s understanding in treatment rules:Whether there is fire or not should be distinguished firstly.Fireless attributes to qi deficiency,some thrombocytopenic patients without bleeding symptoms has fatigue,short of breath and dizziness,which should be treated by qi deficiency theory.Then the excess fire and deficient fire need to be differentiated.The excess fire should apply clearing heat and reducing fire method and the deficient fire should use nourishing yin and reducing fire method,accompanied by dampness should apply clearing fire and dispelling dampness method.The replenishing qi and nourishing yin method,the center of the treatment,should be valued.Meanwhile,professor Feng emphasizes the importance of liver.Liver pertains to wood,if the wood qi is free flow,the blood wouldn’t be stagnated.Fire produced by extreme emotions is one of the most important reasons for PSS,liver qi stagnation transforms to heat and results in bleeding.Combing disease differentiation and syndrome differentiation as well as mastering hemostasis drugs,enhances the hemostasis effect.4.Professor Feng’s medication characteristics in treatment:According to the clinical manifestations,this illness can be concluded into following six syndormes,includes excess heat forcing bleed syndrome,qi stagnation transforming to fire syndrome,dampness-heat syndrome,hyperactivity of fire due to yin deficiency syndrome,qi and yin deficiency,both spleen and kidney deficiency syndrome.The clinical therapy can digest flexible in accordance with different bleeding areas.This dissertation also summarize the common formulas prescribed by Professor Feng in treatment,including Xi Jiao Di Huang decoction,Zhi Bai Di Huang pill,Dan Zhi Xiao Yao powder,Zuo Gui pill,Er Zhi pill,and Sheng Mai powder,Huo Po Xia Ling decoction,and common herbs like radix astragali,Herba agrimoniae,gelatin beads,rhubarb charcoal,selaginella,Ou Jie,crinis carbonisatus.These summaries promote further elaboration of professor Feng’s academic characteristics and medication features in differentiating syndromes and treating of sjogren syndrome with thrombocytopenia.Conclusion1.Professor Feng develops his own academic ideas in sjogren syndrome with thrombocytopenia that qi and yin deficiency is root and excessive dryness-heat is branch.He holds the view that qi and yin deficiency,throughout this illness,is both the primary cause of the disease and the result of bleeding,and excess heat-dryness(or fire)evil is the important pathological factor.2.During treatment,whether there is fire or not should be distinguished firstly.Fireless attributes to qi deficiency.Then excess fire and deficient fire need to be differentiated when there exists the fire,the excess fire should apply clearing heat and reducing fire method and the deficiency fire should use nourishing yin and reducing fire method.The replenishing qi and nourishing yin method is the center of the treatment and the replenish qi and nourish qi method should be valued.At the same time,the importance of liver is emphasized and hemostasis drugs are used flexibly.3.This dissertation analyzes Professor Feng’s opinions of treatment determination based on syndrome differentiation and summarizes common formulas and herbs used in clinical therapy,which further elaborates his academic characteristics and medication features in sjogren syndrome with thrombocytopenia. |