Study On The Characteristics Of Syndrome Differentiation And Distribution Of Parkinson's Disease

Objective:To understand the distribution of six-meridian syndromes and the Formula-Patterns in patients with Parkinson's disease through clinical observation and syndrome differentiation,and to provide a referential path for treating PD with clinical prescription.Methods:Clinical data was collected such as general condition,four diagnostic information,past history.Differentiated the patients by six-meridian,then by Formula-Pattems.Using SPSS statistical software,investigated distribution of six-meridian syndromes and that of Formula-Patterns,as well as the relationship between syndromes of six-meridian and gender and age.Results:1.By six-meridian differentiation,2o types occurred in 181 PD patients,including 4 single meridian diseases and 16 combined meridian diseases.The most common one was Shaoyang and Yangming combined disease,which could be found in 40 patients,accounting for 22.1%,then Shaoyin and Taiyin combined disease had 34 cases,accounting for18.9%,Taiyang and Yangming and Taiyin combined disease had 24 cases,accounting for 13.2%,Taiyang and Shaoyang and Yangming combined disease had 22 cases,accounting for 12.2%,Taiyang and Taiyin combined disease had 12 cases,accounting for 6.6%.But the frequency of Jueyin disease,Shaoyang and Yangming and Taiyin combined disease,Taiyang and Shaoyang Yang combined disease,Taiyang and Yangming and Shaoyin and Taiyin combined disease was less,they only had 1case.Among the 181 patients,Taiyin and its combined disease(including Shaoyang and Shaoyin and Taiyin combined disease,Shaoyin and Taiyin combined disease,Taiyang and Yangming and Taiyin combined disease,etc)are the most common,which had 126 cases;accounting for 69.6%,then Yangming combined disease had 98 cases,accounting for 54.1%,Shaoyang combined disease had 85 cases,accounting for 46.90%,Taiyang combined disease had 80 cases,accounting for 44.2%.2.1n this study,the 181 patients of PD involved 73 Formula-Patterns with the most common one of Chaihujialonggumulitang decoction Formula-Patterns,which had 39 cases,then Zhenwu decoction Formula-Patterns had 25 cases,the others had very less case,amost only 1 case.Among them,Chaihujialonggumulitang decoction and its combined F ormula-Patterns had 43 cases,Zhenwu decoction and its combined Formula-Patterns(including Zhenwu decoction and Sini powder,Zhenwu decoction and Jiegeng decoction and Guizhijiafuzhi decoction,Zhenwu decoction and Jiegeng decoction)had 41 cases,the frequency of them was similar.Chaihu decoction and its combined Formula-Patterns(including Xiaochaihu decoction,Dachahu decoction,Sini power,Chaihujialonggumuli decoction,Chaihujiaguizhiganjiang decoctiond and their combined decoction)had 83 cases,accounting for 45.9%.3.Statistical analysis showed that there was no significant difference between six-meridian syndromes and gender,age.And the main syndromes of PD and past history has no significant influence on the distribution of six-meridian syndrome types yet.Conclusions:1.Combined syndromes are found more commonly than single syndromes.And,each of the combined syndromes has one main syndromes.Shaoyang and Yangming syndromes are the most common type.Combined formulas are found more common than single formulas.Maybe the patients were too less,so that there was no Yangming syndromes and Shaoyin syndromes.2.There was a significant difference in the Formula-Patterns in PD.And Chaihu decoction and its combined Formula-Patterns were used more often than others,especially the Chaihujialonggumuli decoction.3.Chaihuj ial onggumul i decoction;Zhenwu decoction,Guizhijiafuzhi decoction and·Zhenwu decoction are the most common Formula-Patterns.