Analysis Of TCM Syndrome Types And Clinical Features Of Diabetic Foot

Purpose: This research was made to probe the distribution of TCM syndromes in diabetic foot and analyze the relationship between different syndromes and clinical information,lower extremity arterial ultrasound,Wagner grading,efficiency of medical treatment.At the same time,it is also made to provide guidance and help for TCM differentiation and treatment.Material and method:Patients with diabetic foot were collected in Department of Endocrinology in Jinzhou Central Hospital from February 2015 to October 2016.To be dialectical,the results of four diagnostic in TCM were integrated.The clinical information of all patients,including sex,age,course of diabetic,body mass index,WBC count,levels of blood sugar and glucose,lower extremity arterial ultrasound,Wagner grading and effective rate were collected in order to make a retrospective minute.Analyze whether there were differences between different syndromes.Results:1.The distribution of general clinical : The number of male was 1.51 times than that of female,there were 57.89% patients which were older than 60 years old,87.22% patients which were longer than 5 years in DM course,89.47% patients were greater than 25 kg/m2 in BMI.2.Numbers of each TCM syndromes from high to low was blood stasis syndrome,qi and blood deficiency syndrome,hot and humid accumulation syndrome,hot poison yin syndrome,cold dampness barrier syndrome.3.Compared with each syndromes in age,qi and blood deficiency syndrome was eldest,there was statistical differences compered with blood stasis syndrome and cold dampness barrier syndrome(p<0.05).In course of DM term,qi and blood deficiency syndrome was longest,there was statistical differences compered with blood stasis syndrome and hot poison yin syndrome(p<0.05).In terms of BMI,hot and humid accumulation syndrome was highest,there was statistical differences compered with the other four syndromes(p<0.05).4.Compared with each syndromes in WBC count,hot and humid accumulation syndrome was highest,there was statistical differences compered with the other four syndromes(p<0.05).In FPG term,hot and humid accumulation syndrome was highest,there was statistical differences compered with blood stasis syndrome and qi and blood deficiency syndrome(p<0.05).In terms of Hb A1 c,hot poison yin syndrome was highest,there was statistical differences compered with the other four syndromes(p<0.05).5.Compared with each syndromes in TG,cold dampness barrier syndrome was highest,there was statistical differences compered with blood stasis syndrome,qi and blood deficiency syndrome and hot and humid accumulation syndrome(p<0.05).In terms of TC,cold dampness barrier syndrome was highest,there was statistical differences compered with blood stasis syndrome(p<0.05).In HDL-C term,there was no statistical differences between the five syndromes(p>0.05).In terms of LDL-C,cold dampness barrier syndrome was highest,there was statistical differences compered with blood stasis syndrome and hot and humid accumulation syndrome(p<0.05).6.Compared with each syndromes in lower extremity arterial ultrasound,patients with blood stasis syndrome were mainly in mild and moderate group,there was statistical differences when compared with the other four syndromes(p<0.05),while patients with qi and blood deficiency syndrome were mainly in severe and occlusion group,there was statistical differences when compared with the other four syndromes(p<0.05).7.Patients with blood stasis syndrome were mainly in mild level(Wagner 1-2 level)of DF,the differences had statistical significance when compared with the other four syndromes(p<0.05).Patients with qi and blood deficiency syndrome were mainly in severe level(Wagner 3-5 level)of DF,the differences had statistical significance when compared with the other four syndromes(p<0.05).8.In terms of prognosis,the efficient rate of blood stasis syndrome was 85.00%,while qi and blood deficiency was 78.13%,hot and humid poisonous syndrome was72.00%,hot poison yin syndrome was 66.67% and cold dampness barrier syndrome was 79.17%,there was statistical differences between blood stasis syndrome and qi and the other four syndromes(p<0.05).Conclusion:1.Blood stasis syndrome was the common syndrome in TCM,following the others was qi and blood deficiency syndrome,hot and humid accumulation syndrome,cold dampness barrier syndrome.Heat poisoning yin syndrome was the least syndrome.2.Male DM patients with long course of disease,elder age and large BMI may suffered from diabetic foot.3.Blood stasis syndrome was more common in the early stage of DF,and pathological changes of lower extremity arterial ultrasound was mild,the effective rate was the highest.4.Qi and blood deficiency syndrome was more common in the late stage of DF.Patients usually had an elder age,a long course of disease and a serious arterial disease,an obvious lower limb ischemia.5.Patients with hot and humid accumulation syndrome had a bad control of body weight.The degree of infection was the most serious and fasting blood glucose increased significantly.6.The Hb A1 c level of all the patients were increased.Patients with heat poisoning yin syndrome had a higher Hb A1 c and poor blood sugar control.The effective rate was the lowest.7.Most of the patients had dyslipidemia.Patients with cold dampness barrier syndrome usually had a higher triglyceride,total cholesterol and low density lipoprotein cholestero level,so the blood lipids control was worst of all syndromes.