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Different Measures Of Inflammatory Factors In Patients With AS External Counterpulsation Combined With Drug Therapy

Posted on:2017-04-29Degree:MasterType:Thesis
Country:ChinaCandidate:F R ZhangFull Text:PDF
GTID:2354330536469950Subject:Internal medicine
Abstract/Summary:PDF Full Text Request
Atherosclerosis(atherosclerosis,AS)is endangering human health,one of the main diseases,the damage to the cardiovascular and cerebrovascular system can affect the various organs of the body,has become a variety of common diseases in the basic disease.The EECP device is a specially designed air bag cover in the legs,thighs and buttocks of the patient.The diastolic pressure is increased by sequential pressurization of the balloon in the lower body of the human body during the ventricular diastole.Increase myocardial blood supply,improve myocardial ischemia.From January 2012 to May,2016,90 patients with coronary heart disease were selected as the subjects in the Department of Cardiology,Affiliated Hospital of Qingdao University Medical College.According to the digital table method,AS patients were randomly divided into group I(conventional treatment group),group II(short-term anti-stroke group)and group III(long-term anti-stroke group).The levels of serum TNF-? and IL-6 in patients with coronary heart disease before and after treatment were compared,which indicated that the external counter pulsation treatment had the effect of inhibiting inflammation.There were no statistically significant differences between the three groups in the general clinical data,the history of various diseases,and the taking history of all the drugs before treatment(P> 0.05).The sex ratio,age,body mass index,There were no significant differences among the three groups(P> 0.05).There was no significant difference between the three groups(P> 0.05).hsCRP in the three groups were significantly higher than those in the control group After treatment,the levels of TNF-?,IL-6 and hsCRP in group II and III were significantly lower than those in group I(P <0.05),indicating that the longer the treatment time,The better the patient's inflammatory response.External counter pulsation with drug therapy can effectively reduce the serum levels of inflammatory cytokines TNF-?,IL-6,which shows that external counter pulsation treatment of atherosclerosis in patients with inflammation of the inhibitory effect of reducing inflammatory factors in patients with Of the release of vascular endothelial cells in patients with normal function after the protective effect.In addition,external counter pulsation with drug therapy can effectively reduce serum CRP and hsCRP concentrations in patients with serum,further illustrates the external counter pulsation on atherosclerosis has a good therapeutic effect,indicating that external counter pulsation treatment of atherosclerosis Development of a good effect,reduce the patient's clinical symptoms and pain,improve the quality of life of patients and survival.
Keywords/Search Tags:Atherosclerosis, External counter pulsation, Drug therapy, Inflammatory factors
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