The Effect Of Bilateral Upper Limb Training On Recovery Of Upper Extremity Motor Function After Cerebral Infarction Was Observed Based On Bold-fMRI

Objective:To study the recovery situation of upper limb motor function in patients after ischemic stroke with bilateral upper extremities training technique by restorative functional magnetic resonance imaging(rs-f MRI).And obverse the relationship with the clinical rehabilitation rating scale.And to provide theoretical and technical support for the rehabilitation of patients with ischemic stroke.Methods: The inpatients in the rehabilitation department of the People's Hospital of Sichuan Province were screened according to the screening criteria of this experiment.Twenty patients who met the standard were selected.And the twenty patients were randomly divided into two groups: the upper limb treatment group(contains 6 males and 4 females)and the control group(contains 5 males and 5 females).All patients were treated with conventional physical therapy,occupational therapy,acupuncture and other conventional treatment,Unilateral and bilateral upper limb training group on this basis to give a unified development of upper limb motor technology.The training period is one month,once a day.The All patients were admitted to the hospital for admission to the upper limb function score(Fugl-Meyer upper limb motor function assessment),conventional T1WI(T1 weighted imaging,T1 weighted imaging),T2WI(T2 weighted imaging,T2 weighted imaging)and resting functional magnetic resonance Scan(rs-f MRI),after a month of treatment,again assessed and scanned.The data and images were analyzed by Matlab2012 a.The Reho and Alff values of the primary motor cortex(M1)region were measured before and after treatment.Finally,REST was included in the statistical analysis.Results: 1.After treatment,both patients in the upper limb treatment group and the control group had increased Reho activation in the ipsilateral M1 region,and the bilateral treatment group increased more(p<0.05).2.The Alff values in the ipsilateral M1 region of the bilateral upper limb treatment group were significantly lower than those in the control group(p<0.05).3.The changes of Re Ho and Allf in the ipsilateral M1 area were positively correlated with the changes of the clinical limb function score(Fugl-Meyer)before and after treatment,and there was a positive correlation with the bilateral upper limb treatment group.The correlation coefficient of ?Re Ho and ?Fugl-Meyer r = 0.793(p = 0.006),?Alff and ?Fugl-Meyer correlation coefficient r=-0.837(p=0.003)in the bilateral treatment group,and the correlation coefficient r=0.647(P=0.043),? Alff and ?Fugl-Meyer correlation coefficient r =-0.764(p = 0.01).Conclusions: Bilateral upper limb training in the rehabilitation of upper limb motor function in patients with cerebral infarction than the traditional only for unilateral upper limb therapy more effective;Re Ho and Allf can be used as functional magnetic resonance imaging to observe the post-cerebral infarction upper limb motor function rehabilitation indicators.