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Economic Evaluation Of Type 2 Diabetes Based On Net Benefit Regression Analysis

Posted on:2018-12-08Degree:MasterType:Thesis
Country:ChinaCandidate:Q Q KangFull Text:PDF
GTID:2354330515991874Subject:Social Medicine and Health Management
Abstract/Summary:PDF Full Text Request
Objective:To extract the medical records of a hospital endocrine department from January 2014 to June 2016 and a hospitalized course of 10-20 days in type 2 diabetes patients based on retrospective studies and based on baseline irregularities.This paper constructs a framework for the evaluation of the economic economics of the net benefit as the output index,and then carries out the drug economics evaluation on the net benefit regression framework to the extracted medical records,and use the net benefit regression analysis to explain the economic differences between the two treatment programs,for the decision makers to develop prices and patients with type 2 diabetes to provide treatment and recommendations.Methods:By searching the CNKI,Wanfang,Weipu,SPringer and other databases and search engines such as Baidu and Google,we searched for "type 2 diabetes","drug economy","net benefit regress","cost-effect" as the key words,access to the relevant literature of the type 2 diabetes drug economics and net benefit framework,and using the method of the field research to obtain the relevant data,and carrying on cost-effect analysis and net benefit analysis for the collected data based on retrospective research.Content:First of all,we can give the Baseline data analysis,Cost analysis,Effect analysis,Cost-effectiveness analysis and Incremental analysis of the organized data of 136 cases.Then we could introduce the numerical value that patients willing to pay,using regression analysis method,and conduct the net benefit regression analysis of the whole sample and subgroup of the treatment scheme of A,B two groups,in order to compare the Pharmacoeconomic differences between the two groups.Finally,we should carry on the sensitivity analysis for ?,the numerical value that patients willing to pay,in order to determine the numerical value that patients willing to pay and the decision credibility,and try to draw the ?-? Acceptable curve at the same time.Result:when we deem HbA1c as the explanatory variable:if belongs to section(1242.325,?),belongs to section(0,161.67),that means process B can produce more net benefit than A,and belongs to section(-162.69,95.96);if belongs to section(0,1242.32),belongs to section(-116.7,0),? belongs to section(338.16,?),that means process A can produce more net benefit than B.When we deem 2hPBC as the explanatory variable:if belongs to section(338.16,?),belongs to section(0,95.96),that means process B can produce more net benefit than A;if belongs to section(0,338.16),belongs to section(-4619.3,0),that means process A can produce more net benefit than B.When we deem FBG as the explanatory variable,if belongs to section(0,413.9),belongs to section(0,113.72),that means process B can produce more net benefit than A.Conclusion:For all the samples,when the explanatory variable is HbA1c,we should choose scheme B for it is more economical if ?0(1242.32 yuan);Similarly,we should choose scheme A for it is more economical if ?0(1242.32 yuan).When the explanatory variable is 2hPBC,we should choose scheme B for it is more economical if ?0(338.16 yuan);Equally,we should choose scheme A for it is more economical if ?0(338.16 yuan).When the explanatory variable is FBG,we should choose scheme B for it is more economical if ?0(2381 yuan);In the same way,we should choose scheme A for it is more economical if ?0(2381 yuan).In the analysis of subgroup,we analyzed 42 cases with other chronic diseases.Among this,when the explanatory variable is HbAlc,we should choose scheme A for it is more economical if ?0(162462.48 yuan);Similarly,we should choose scheme B for it is more economical if ?0(162462.48 yuan).When the explanatory variable is 2hPBC,we should choose scheme A for it is more economical if ?0(416.07 yuan);Equally,we should choose scheme B for it is more economical if ?0(416.07 yuan).When the explanatory variable is FBG,we should choose scheme A for it is more economical if?0(9086 yuan);In the same way,we should choose scheme B for it is more economical if ?0(9086 yuan).
Keywords/Search Tags:Type2diabetes, Cost-effectiveness, Net-benefitregression, Retros pective study
PDF Full Text Request
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