| Macleyea cordata(Willd)R.Br.,a plant belonging to genus of Macleaya,papavcreraceae family,is a perennial tall erect herb,mainly distributed in Southeast Asia and China,and in our country is distributed in Hunan,Anhui,Jiangsu and other provinces.This plant has effects of antibacterial,antiinflammatoary,insecticidal,and so on.Modern studies show that many papers on chemical and pharmacological research of M.cordata have reported that it contained many kinds of components,especially isoquinoline alkaloids as its main components.For promoting the medicinal development of Macleaya cordata,enriching the diversity of chemical ingredients from the medicinal resource and finding more alkaloids from various organs of Macleaya cordata,the chemical constituents of the extract from the leaves and root of Macleaya cordata.Using LC-MS to determine the separation target,the chemical ingredient were isolated and purified by Modern chromatographic separation,and the structures were elucidated based on the spectral data.The structures of ten compounds were identified as: N-methylscoulerine(1),6′-hydroxy-2′,3′-dimethoxyarnottianamide(2),Norchelerythrine(3),6-methoxyldemethylsanguinarine(4),6-hydroxymethyldihydrosanguinarine(5),7-demethyldihydrochelerythrine(6),Nandinine(7),parahydroxyben-zaldehyde(8),2,2-dimethoxyacetic acid(9),Resveratrol(10).Compounds 1 and 2 are new compounds,compounds 3~10 are isolated from this plant for the first time. |
