Clinical Study Of The Effect Of Egg Soup On The Intervention Of IVF-ET Ovarian Hyporesponsiveness

Objective: The clinical observation of the effect of the treatment of the patients with low response to the treatment of the patients with low ovarian response in the embryo transfer. From the endometrial thickness, endocrine level, egg number, good quality embryo rate and pregnancy rate of study helps the eggs soup to improve the curative effect of ovarian response, clear egg soup to participate in the feasibility and effectiveness of the auxiliary IVF-ET, and for traditional Chinese medicine in assisted reproductive technology to provide objective data and theoretical basis.Methods: This study adopted randomized control method, will meet the inclusion criteria of 80 cycles of treatment were divided into 2 groups, whether to add service help Chinese egg soup as auxiliary treatment for treatment group(helps the eggs Decoction with western medicine group) 40 cycles of treatment and control group(Western medicine group) 40 treatment cycle. Control group by mini stimulation protocol, namely menstrual 3-7 days daily oral clomiphene citrate 50 mg, menstruation the 5 daily injections of HMG75--150 UI, until h CG day. In the treatment group, second days in the menstrual cycle, and served to help the egg soup, a daily dose, and even served 10 days. The two groups were detected by transvaginal B ultrasound recording of follicular growth and the determination of hormone(P, LH, E2) level, the control group according to follicle growth and hormone changes in the body to adjust HMG dosage. When the average diameter, more than 18 mm follicular accounted for "14mm follicles of more than 60% above or on the day of h CG LH" 10IU/L is the next day review LH, E2, if E2 entered platform stage, intramuscular injection of HCG10000 U. The eggs were obtained by transvaginal ultrasound within the HCG30-36 hours of injection. To observe the two group patients were injected with h CG, uterine endometrial thickness, on the day of h CG, 16 mm follicle number, on the day of h CG E2 value, HMG dosage and number of days, the egg number, number of embryos, good quality embryo rate, biochemical pregnancy rate, clinical pregnancy rate, TCM syndrome of kidney deficiency syndrome, and integral etc. related factors of influence.Results: 1 basic clinical data of IVF The treatment group and the control group of h CG on uterine endometrial thickness, on the day of h CG, 16 mm follicle number, on the day of h CG E2 values, HMG dosage and number of days, the number of oocytes, the number of embryos, high quality embryo rate, biochemical pregnancy rate, clinical pregnancy rate, TCM Syndrome of kidney deficiency syndrome, and integral, is statistically significant(P < 0.05), in the treatment group than the control group. 2 clinical symptoms Treatment group menstruation to be not moved, menstrual dark, waist sacral acid, dizziness, tinnitus, mental fatigue, sexual apathy, vaginal dryness kidney qi deficiency symptoms improved significantly, and compared with the control group(P < 0.05), the treatment group was significantly better than the control group.Conclusion: 1 helps the eggs soup can effectively reduce the patients with poor ovarian response of menstruation is not moved, menstrual dark, waist sacral acid, dizziness, tinnitus, mental fatigue, sexual apathy, vaginal dryness and other symptoms of kidney deficiency. 2 IVF-ET can reduce the dosage of HMG and the number of days, increase the number of eggs, increase the number of eggs, improve the quality of embryos, and ultimately improve the clinical pregnancy rate. 3 can effectively improve the micro stimulation program caused by the thin film of the thin film, is conducive to the transfer of embryos, increase the pregnancy rate.