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Analysis Of Carotid Plaque In Tibetan Patients With Coronary Atherosclerosis In Qinghai Area

Posted on:2019-01-23Degree:MasterType:Thesis
Country:ChinaCandidate:Z L LiFull Text:PDF
GTID:2334330569997591Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
Objective:The characteristics of carotid artery plaques in the Tibetan patients with coronary atherosclerosis in qinghai region were analyzed with3.0t high resolution magnetic resonance imaging.Methods:The 114 cases of the selected Tibetan patients were grouped according to the degree of coronary stenosis,atherosclerotic group26 cases(coronary atherosclerosis,and the degree of coronary stenosis<50%);single vessel group 47 cases(1 degree of coronary artery stenosis more than 50%);multi vessel group41 cases(2 or 3 branches of coronary artery stenosis more than 50%).The carotid artery high resolution magnetic resonance(3.0T)scan was performed in 114 cases of the Tibetan patients,and the characteristics of carotid artery plaque in the 3 groups of Tibetan patients were compared.Results:1?Three groups of Tibetan patients had no significant difference in age,sex,BMI,smoking history,drinking history,hypertension history,dyslipidemia history,diabetes history and statin use history(P>0.05).2?(1)There was no significant difference in plaque and calcified plaque detection rate between the three groups(P>0.05).(2)The three groups of carotid plaque lipid rich necrotic core inspection rate have significant difference(P<0.05),atherosclerosis group the detection rate of LRNC(30.7%)and single vessel group the detection rate of LRNC(63.8%)with significant difference(P<0.0125),atherosclerosis group the detection rate of LRNC(30.7%)multivessel disease group detection rate of LRNC(70.7%)with significant difference(P<0.0125),single vessel group the detection rate of LRNC(63.8%)and multi branch lesion detection rate of LRNC(70.7%))no significant difference(P>0.0125).(3)No hemorrhage in plaque was detected in atherosclerotic group and single vessel group,and multi vessel group could be detected(7.3%).(4)There were no plaque ulcers in the carotid arteries of the three groups of Tibetan patients.(5)The degree of carotid plaque severity is positively and slightly positively correlated with the degree of coronary artery disease in Tibetan(r_s=0.297,P=0.001).Conclusions:The characteristics of Tibetan carotid plaque may be related to the severity of coronary atherosclerosis.With the severity of carotid plaque changes,the degree of coronary arteriosclerosis may worsen.
Keywords/Search Tags:Tibetan nationality, Coronary atherosclerosis, Carotid atherosclerosis, High-resolution magnetic resonance
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