Prognostic Analysis Of 117 Patients With Acute Pulmonary Embolism

Object By analyzing the risk factors of acute pulmonary embolism in different conditions and the correlation of clinical criteria,to explore its role in disease progression and prognosis,it provides a reasonable reference for early diagnosis and prognosis evaluation of the disease.Method The medical records of 117 patients with acute pulmonary embolism who were admitted to the General Hospital of Ningxia Medical University from March 2014 to March2017 were collected.According to the Simplified Pulmonary Embolism Severity Index(sPESI)score,the patients were divided into sPESI high-risk group and low-risk group.There were 57 high-risk patients,including 32 males and 25 females,and 60 low-risk patients,including 30 males and 30 females.By analyzing the general clinical data,blood routine,blood biochemistry,and a full set of blood coagulation indexes in the two groups of patients,whether the above-mentioned indicators have statistical differences between the two groups of patients was compared.Results There were significant differences in systolic blood pressure(P<0.05),diastolic blood pressure(P<0.05),heart rate(P<0.001),transcutaneous oxygen saturation(P<0.001),serum sodium(P<0.001),total cholesterol,arterial partial pressure of oxygen(P<0.001),etc.There was a significant difference among smoking groups,which showed that the smoking rate was higher in the high-risk group than in the low-risk group(P<0.05).The hospital mortality in high-risk group was higher than that in low-risk group.Logistic univariate regression analysis revealed that heart rate,systolic blood pressure,diastolic blood pressure,percutaneous oxygen saturation,red blood cells,platelets,serum sodium,and in-hospital mortality were significantly correlated(p<0.05).Logistic multivariate regressionanalysis revealed that transcutaneous oxygen saturation(OR: 0.8844;95% CI: 0.7868-0.9940)and serum sodium(OR: 0.7843;95% CI: 0.6245-0.9850)were influential factors for in-hospital mortality in patients with acute pulmonary embolism.Conclusion(1)Smoking is a risk factor that influences the incidence of acute pulmonary embolism.(2)The determination of plasma D-dimer contributes to the diagnosis of acute pulmonary embolism,but its level is not significantly related to the prognosis of pulmonary embolism.(3)The negative correlation between transcutaneous oxygen saturation and serum sodium levels is an important risk factor influencing in-hospital mortality in patients with pulmonary embolism.It plays an important role in early identification of pulmonary embolism and reasonable prognosis assessment.