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Experimental Study Of Fluroscopic Stereophothogrammetric Analysis (FSA) In Aseptic Loosening Of Prosthesis

Posted on:2019-03-28Degree:MasterType:Thesis
Country:ChinaCandidate:H YangFull Text:PDF
GTID:2334330566962817Subject:Biomedical engineering
Abstract/Summary:PDF Full Text Request
The aseptic prosthesis loosening is one of the most important causes for prosthesis failure and revision after artificial joint replacement.At present,the stability of artificial joint with aseptic loosening can only be restored through revision surgery.Artificial joint revision surgery will impose a great physical and economic burden on the patient.To ensure the safety of patients,the assessment of the quality and safety of artificial joint prostheses is very important.It has been determined that the early migration of joint prostheses after arthroplasty can predict the trend of late aseptic loosening.The early diagnosis of aseptic loosening of the prosthesis is an effective means to evaluate the long-term implantation performance of the prosthesis,and can effectively prevent the inferior prosthesis from causing greater harm.In this paper,the Fluoroscopic Stereophotogrammetric Analysis(FSA)technology based on 2D-3D registration was used to analyze the early migration of artificial joint prosthesis.The main principle of this method is to perform 2D-3D registration using the 2D fluoroscopic images and the 3D models reconstructed from CT data,so as to obtain the relative displacement changes between the prosthesis and the bone at different time periods within two years after the joint replacement.At present FSA analysis has problems such as software mismatch and low accuracy.This article uses digitally reconstructured radiograph technology to design a 2D-3D registration software.Gradient correlation is used as a similarity measure function,combined with the Levenberg-Marquardt optimization algorithm.This paper examines the effects of the two methods of object-centered and camera-centered and different initial conditions of registration on the registration results.The 2D-3D analysis software designed by this project is fully in line with the existing clinical requirements through image synthesis experiments and three-dimensional loosening model validation,and is simple and convenient,with high accuracy,and is convenient for clinical use.It is based on the hospital's existing equipment to collect data for analysis,which contributes to its clinical application and promotion in the country.The analysis system established in this project is helpful to establishing the principle of clinical experiment grading review of artificial joint prosthesis,screening the inferior prostheses whose safety and effectiveness are not up to standard,and ensuring the safety of patients.In addition,a simulated biplane Fluoroscopic Stereophotogrammetric Analysis(FSA)analysis method is also proposed in this paper.The biplane fluoroscopic stereophotogrammetric analysis has high precision,but the current popular biplane perspective analysis method has high requirements for equipment and is not conducive to clinical application.This subject originally designed a simulated biplane fluoroscopic stereophotogrammetric analysis technology for the early migration analysis of artificial joint prosthesis,which has lower requirements on equipment and improved accuracy.
Keywords/Search Tags:Artificial joint prosthesis, Aseptic loosening, Early migration, Fluoroscopic Stereophotogrammetric Analysis, Accuracy verification
PDF Full Text Request
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