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To Evaluate The Predictive Value Of AMH And FSH In Pregnancy Outcomes In Patients With IVF-ET

Posted on:2019-03-08Degree:MasterType:Thesis
Country:ChinaCandidate:F K ZhuFull Text:PDF
GTID:2334330548456394Subject:Obstetrics and gynecology
Abstract/Summary:PDF Full Text Request
Objective:To analyze the value of anti-Mullerian hormone(AMH)and follicle-stimulating hormone(FSH)in assessing ovarian reserve and predicting pregnancy outcomes in patients with IVF-ET.Methods: A total of 120 patients with AMF and FSH were enrolled in this study.The AMH and FSH levels in group A were AMH <1.1 ng / ml;bFSH <10 IU / L,B group: AMH> 1.1ng / ml;bFSH> 10 IU / L,all parameters related to IVF-ET in both groups were recorded: age,BMI,hormone level,basal antral follicle count(AFC),luteinizing hormone(LH),estradiol level,amount of gonadotropin(Gn),number of oocytes retrieved,number of mature eggs,number of fertilized eggs,number of cleavage and number of high quality embryos were analyzed statistically.Then the patients were divided into two groups according to whether the IVF-ET treatment outcome was clinical pregnancy,that is,the clinical pregnancy group and the non-clinical pregnancy group.The influencing factors of IVF-ET treatment of clinical pregnancy outcome were analyzed.Results: The basal antral follicle count(AFC)and the number of oocytes retrieved,the number of fertilization and the number of high-quality embryos in group A and group B were significantly different(P<0.05).The age of group A was greater than that of group B.The total amount of Gn used was more than that of group B,but there was no statistical difference(P>0.05).The AMH blood levels in the clinical pregnancy group were higher than the AMH blood levels in the non-clinical pregnancy group,and the difference was statistically significant.The clinical pregnancy group had more transplantable embryos and higher quality embryos than the non-clinical pregnancy group.Statistically significant,there was no statistically significant difference in the number of antral follicles,the total amount of Gn,the total number of eggs obtained,and the number of fertilization between the two groups.Conclusions: In infertile patients who undergo IVF-ET therapy when their ovarian function indicators are inconsistently monitored,their AMH levels predominate in predicting ovarian function and responsiveness,but they do not directly reflect clinical pregnancy outcomes.They can be used as individualized ovulation-promoting programs.The establishment of indirect predictors of prevention of COH-related complications can be used as a predictor of better assisted reproductive outcomes and clinical pregnancy outcomes in some women of childbearing age.
Keywords/Search Tags:Anti-Mulleria hormone, Assisted reproductive technology, Follicle-stimulation hormone, In vitro fertilization and embryo transfer
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