| THE DISTRIBUTION OFCEREBRAL VASCULAR HEMODYNAMIC INDEX IN ELDERLY PATIENTS WITH HYPERTENSIONObjective:to investigate the distribution of cerebral vascular hemodynamic index(CVHI)in elderly patients with hypertension.Methods:this study was a cross-sectional study.117 cases of elderly patients with essential hypertension were selected in the retried persons from November 2016 to May 2017.1n addition,111 cases of retired non-hypertension elderly patients who were treated at WuYunshan Sanatorium during the same period were selected as the control group.General data collection,laboratory examination and CVHI detection were conducted to analyze the overall level of CVHI and the horizontal distribution of each indicator.Results:the abnormal rate of CVHI was 45.3%in hypertension group.Compared with the control group,the hypertension group average flow rate,average flow velocity,maximum velocity,the minimum flow rate significantly lower,pulse wave velocity,characteristic impedance,peripheral resistance,dynamic resistance,differential pressure significantly higher(P<0.05).Conclusion:cerebral hemodynamics is abnormal in elderly patients with hypertension,in addition,the blood flow velocity and other indicators of cerebral blood vessels showed a decreasing trend,and the peripheral resistance and other indicators showed an upward trend.EFFECT OF CVHI ON MILD COGNITIVE IMPAIRMENT IN ELDERLY PATIENTS WITH HYPERTENTIONObjective:To study the relation between CVHI and Mild cognitive impairment(MCI)in elderly patients with hypertension.Methods:117 primary hypertension patients were included in this study and divided into primary hypertension group with abnormal CVHI score(<75)(group 1,n=53)and primary hypertension group with CVHI score(≧ 75)(group 2,n = 64).111 volunteers who underwent health check served as a control group.Their cognitive function assessment was tested according to the Moca scale.Results:The total Moca score and Visual space and executive function item,language,delayed memory score in group 1 and group 2 were lower than control group.The total Moca score and abstract,delayed memory score in group 1 were lower than group 2(p<0.05,p<0.001).Logistic regression analysis showed that Vmin isaprotective factor for cognitive function(β=0.698,p=0.023),primary hypertension group with abnormal CVHI score(<75)(β=4.809,p<0.001),CVHI score(<75)(β值=1.23P=0.004)),Low years of education<12(β=2.098,p=0.021),diabetes(β=2.540,p=0.037)were independent risk factors for MCI occurrence in elderly patients with hypertension.Conclusion:in addition to the traditional education age,diabetes impact factors,in elderly patients with hypertension combined CVHI exceptions are independent risk factors for mild cognitive dysfunction,the greater influence on the occurrence and development of MCI. |
