| Objective LPRD is a clinically common disease in the otolaryngology department.The western medicine treatment method is relatively simple and the curative effect is not exact.At present,Chinese medicine has a unique theoretical system and good curative effect on LPRD,but its research on dialectical classification is more general.In particular,the observation of clinical dialectical treatment of common symptoms and syndromes remains to be improved.Therefore,we decided to proceed with the study.The short-term,long-term clinical efficacy and adverse events of Dangshushufang combined with pharyngeal cryotherapy for liver-gastric discordant LPRD.Methods Selection in February 2017 to February 2018 in the first hospital in wuhan city and accord with LPRD,western medicine diagnosis of 72 cases of patients,according to random number table method were divided into treatment group and control group(n = 36,eliminate cases treatment group 35 examples after fall off in 5 cases,control group 32 cases.To be oral treatment group the pharynx ShuFang(wuhan first hospital of TCM pharmacy + pharyngeal spray freezing treatment,the control shall be LanQin oral liquid(10 ml/teams,Yangtze river pharmaceutical group co.,LTD.Produces Z19991005)approved by the + pharyngeal spray freezing treatment,drug usage: since the pharynx ShuFang water decoction,400 ml/agent,the agent of 1 / d,three times in three meals take half an hour after a meal,2 weeks as a course;Oral administration of lanqin oral solution,20ml(2 pieces)/time,3 times /d,2 weeks as 1 course of treatment;The pharyngeal spray was frozen every 3~5d lines 1 time,3 times as 1 course of treatment;All three treatments are treated with at least one course of treatment.If the patient reaches the "cure" level after 1 course of treatment,no further treatment is required,otherwise the treatment will continue for 1 course of treatment.RSI and RFS scores were recorded before and after treatment for 2 weeks after treatment and 1 month after treatment,and RSI score was used as the main therapeutic evaluation criteria.Results There was no statistically significant difference between the two groups in age,duration of onset,gender,smoking and alcohol history,and Hp positive difference(P BBB 0.05).Comparison between the two groups during the same period: 2 weeks after treatment,the RSI score and total efficiency of the treatment group were significantly different from those in the control group(P<0.05).After treatment,the RSI score,total efficiency,efficiency and efficiency of the treatment group were significantly better than those in the control group(P<0.05).In different periods within the same set of comparison: 2 weeks after treatment and treatment of the two groups were no significant differences of each value and the rate(P>0.05),but the treatment group after treatment and treatment before January RFS score,score RSI,effective,efficient significant difference(P<0.05),while the control group both in 2 weeks or 1 month after treatment,after treatment compared before treatment rate of each value and no significant difference(P>0.05).Adverse reactions in the treatment group were 2(5.71%),and 4 cases(12.5%)in the control group showed mild symptoms and gradually improved or disappeared after stopping the drug,adding or subtracting the drug or treating the disease.Conclusion Through the clinical observation and research of this topic,we conclude that whether it is a self-made Yanshu prescription + pharynx spray freeze-thaw treatment,or Banlangen mixture + pharynx spray freeze-thinking treatment,both LPDD and yin deficiency type LPRD patients can be made.Significant improvement in clinical symptoms,while the former is far superior to the latter in both short-term and long-term outcomes(P<0.05),and there are no obvious adverse reactions and high safety.It provides new ideas and new insights for the currently unsuccessful research on syndrome differentiation and treatment of LPRD.Methods;At the same time,liver and stomach deficiency and yin deficiency syndrome can be used as a standard reference for diagnosis and treatment of LPRD virtual inclusion syndrome. |
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