The Effect Of Computer-assisted Cognitive Training Based On Information Processing Theory In Post-Stroke Cognitive Impairment

Objective:To explore effectiveness of cognitive rehabilitation training system is based on information processing theory on cognitive function and activities of daily living in patients with cognitive impairment after stroke through randomized controlled design.Method:According to inclusion and exclusion criteria,a total of 60 eligible subjects were randomly allocated into experimental group or control group,so that there were 30 in each group.Subjects in experimental group were given the computer cognitive rehabilitation training and in control group were given the conventional cognitive training.The intervention time was 4 weeks,5 times a week,each time 30min.The outcomes include:?1?the global cognitive function was evaluated with Montreal Cognitive Assessment?MOCA?;?2?the attention function was evaluated with Digital Span?DS?,Symbol digital modalities test?SDMT?and Digital vigilance test?DVT?;?3?the memory function was evaluated with Chinese auditory learning test?AVLT?;?4?the executive function was evaluated with Trail making test?TMT?;?5?the ability of daily life was evaluated with Modified Barthel Index?MBI?and Lawton Instrumental Activity of Daily living?Lawton IADL?.Primary and secondary outcomes will be measured at baseline and the end of the intervention,respectivelyResults:1.The baseline results showed that there were not statistical differences between 2 groups in gender,age,course of disease,education,type of stroke,hemiplegia?P>0.05?.Similarly the global cognitive function attention,memory,executive function and ability of daily life had no statistical differences between groups before intervention?P>0.05?.2.The global cognition function of two groups were improved after post intervention and the difference between two groups has statistical significance?P<0.05?;Compared with the control group,patients in the experimental group with MOCA score was not improved?P>0.05?.3.The DS-forward,DS-backward,DVT,SDMT of two groups were significantly improved after post intervention,and the difference between two groups has statistical significance?P<0.05?;Compared with the control group,patients in the experimental group with the DS-forward and SDMT were significantly improved and the difference has statistical significance?P<0.05?₄.The score in AVLT of two groups were improved after post intervention and the difference between two groups has statistical significance?P<0.05?;Compared with the control group,patients in the experimental group with the AVLT had significantly changes were observed between the two groups post-intervention?P<0.05?.5.The TMT-A,TMT-B of two groups were significantly improved after post intervention and the difference between two groups has statistical significance?P<0.05?;Compared with the control group,patients in the experimental group with TMB had the significant changes were observed between the two groups post-intervention?P=0.021?.6.The MBI of two groups were significantly improved after post intervention,the difference between two groups has statistical significance?P<0.05?,but Lawton IADL had no significant changes were observed;Compared with the control group,patients in the experimental group with MBI had no the significant changes were observed between the two groups post-intervention?P>0.05?.Conclusion1.Patients with cognitive impairment after stroke underwent 4 weeks of computerized cognitive rehabilitation training and conventional cognitive training,both of them were improved cognitive function.2.The effect of computerized cognitive rehabilitation training in executive function,attention function and memory function in is better than the conventional cognitive training.