| Objective:To evaluate the curative effect of "Ningxinshen" formula on chronic heart failure patients with sleeping disturbance(deficiency of both qi and yin),treating them of this formula,to explore the effect of sleeping quality?TCM clinical presentation scale and the symptoms of heart failure?Method:40 cases of CHF patients with sleeping disturbance were collected in general survey study.Divide the 40 cases into control group and treatment group with 20 cases each.The control group was treated by western medicine routine on heart failure;the treatment group was given "Ningxinshen" formula and conventional therapy at the same time.Before and after an observation period of 14 days,record the scores of PQSI,clinical presentation and medical laboratory indexes of the both two groups.Statistic analysis was applied to evaluate the efficacy and differences of "Ningxinshen" formula and western medicine routine.Result:1?The comparison of the PQSI scores:In pretherapy and post-treatment,the PQSI scores reduced with statistical significant(P<0.05)in treatment group;In control group,the PQSI scores were declined as well,there is no difference(P>0.05)in statistic though.The "Ningxinshen" goup is much better than the other group in reducing the PQSI scores after the research and the difference is statistically significant(P<0.05).2?The comparison of TCM clinical presentation of the two groups:In "Ningxinshen"goup,the scores reduced from 15.45±1.986 to 10.95±2.395 significantly in statistics after treatment(P<0.05);meanwhile the control group did not changed obviously as the scores declined from 15.40±2.521to 14.85±2.5813?The comparison of curative effective between the two groups:The efficient cure rate of"Ningxinshen" goup reached up to 95%,relatively 90%by the control group.The difference is statistically significant in therapeutic effect(P>0.05).4.The comparison of NT-proBNP:NT-proBNP of the two groups both declined with statistical significant,while there is no statistically significantly difference between the groups in the degree of decent.Conclusion:1?Treating the CHF patients troubled by sleeping problems with "Ningxinshen"formula on the basis of western medicine routine,significantly improves sleeping quality?TCM clinical presentation and symptoms than conventional therapy alone.2?The "Ningxinshen" formula can improve sleeping quality and clinical presentation of CHF patients at a certain extent.It deserves to be promoted clinically as the good safety performance. |
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