Effect Of Sancai Combinative Acupoints And Baihui Acupoint On Sleep Diary?TPF And ET In Patients With Primary Insomnia

Purpose:The research disease is the primary insomnia,and carries on the standardized inclusion and the elimination to the clinical primary insomnia patient.Using electroacupuncture respectively stimulate the single acupointor the compatibility acupoints to treat primary insomnia,and observing the differences of two methods for patients on ET?TPF and their sleep diaries.Then evaluating the clinical curative effect for treating primary insomnia by electroacupuncturing single point or compatibility acupoints.And then providing a scientific basis for the compatibility acupoints theory and clinical prescription of acupuncture for treating primary insomnia.Method:In this study,the primary insomnia patients as the research object,using of randomized controlled trial as the design method.In the trial,72 patients were randomly divided into two groups according to the order of visit:the single point group and the compatibility acupoints group,36 cases in each group.Using single blind method to study evaluation.The object of blinding.Treatment methods: The treatment group of single acupoint use Baihui(single),the treatment group of compatibility acupoints use Baihui,Shenmen(double)and Sanyinjiao(double).Patients were maintained at supine position,after acupuncture,using electroacupuncture stimulate the acupoints.The electroacupuncture is set to continuous wave 60 Hz,30min,5 days for 1 courses,and 2 days interval,continuous treatment of 5 courses.Follow and record the therapeutic effects after the end of treatment.Using sleep diaries as the objective indexes,IS and TPF as the Subjective index.Excel is selected to carry on the preliminary statistics of the data,statistical analysis of the statistical data by SPSS19.0 software,To collect the relevant data,summarize the difference of clinical curative effect.Result:1.Sleep diaries result:a.In single point group,during the treatment period,there are differences in the time of fall asleep and total sleep time,total sleep quality was different from that before treatment(P<0.05);b.In combinative acupoints group,during the treatment period,there are significant differences in the time of fall asleep,total sleep time,total sleep quality was significantly different from that before treatment(P<0.01);c.The two groups of patients after treatment,in the time of fall asleep,total sleep time,total sleep quality have significant difference(P<0.01).2.TPF record result: a.In single point group,during the treatment period,there are differences in deep sleep time and total sleep time,the score was different from that before treatment(P<0.05);b.In combinative acupoints group,during the treatment period,there were significant differences in the 3 factors in TPF(P<0.01);c.The two groups of patients after treatment in deep sleep time,total sleep time and the score etc.have significant difference(P<0.01).3.ET detection result: a.In single point group,compare neurotransmitter value before and after treatment,GABA?Glu ?Ach?DA and NE have a difference(P<0.05),while 5-HT have an extremely significant difference(P<0.001);b.In combinative acupoints group,,compare neurotransmitter value before and after treatment,Ach have a difference(P<0.05),GABA,Glu and NE have a significant difference(P<0.01),while 5-HT and DA have an extremely significant difference(P<0.001);c.The two groups of patients after treatment,5-HT have significant difference(P<0.01),GABA,Glu,Ach,NE,DA content also have a difference(P<0.05).4.The overall clinical efficacy:single point group 36 cases,5 cases were cured,7 cases were markedly effective,effective in 12 cases,7 cases were ineffective,5 cases fell off,the total efficiency of 66.67%.And compatibility acupoints group 36 cases,10 cases were cured,14 cases were markedly effective,effective in 6 cases,3 cases were ineffective,3 cases fell off,the total efficiency of 83.33%.There has difference between the two groups(P=0.025 < 0.05).Conclusion:Single point acupuncture and combination of acupoints for treating primary insomnia are both effective,but the effect of compatibility acupoints group is better than the single point.