Research Of Myocardium Strain In Patients With Myocardial Hypertrophy By 2D-Speckle Tracking Imaging

Objective 1.To measure systolic peak strain and assess the myocardial strain in patients with myocardial hypertrophy by two-dimensional speckle tracking imaging.2.To analyze the correlation between the regional myocardial funcation and myocardial strain,to explore the value of evaluating the regional myocardial funcation in patients with myocardial hypertrophy by two-dimensional speckle tracking imaging.Methods 1.Object 30 subjects were included in the normal control group,30 patients with hypertension heart,30 patients with diabetic cardiomyopathy and 30 patients with hypertrophic cardiomyopathy were enrolled in the study.2.Equipment Philip IE33 color echocardiography imaging system with S5-1 probe and QLAB work station,the frequency of the probe is l.5~3.0 MHz.3.Measurement Measuring the interval thickness by using two-dimensional echocardiography,calculated the left ventricular ejection fraction(LVEF)using Simpson biplane method.All the subjects underwent conventional echocardiography,and to analyzed the dynamic image in three cardiac cycle by using QLAB work station,the system gives the myocardial strain and strain curves automatically.Observation and recording the systolic peak strain(Ss)of each cardiac cycle,Each take the average of three measurements.Compare the characteristics of hypertrophy myocardial strains in different types of heart disease patients,discuss the correlation between systolic peak strain(Ss)and left ventricular ejection fraction(LVEF).Results 1.The age?heart rate and LVEF had no significant cdifference among the four groups.(P>0.05).2.Compared with control group,the IVS were significantly higher in the other three groups(P <0.05).There were no significant difference in IVS between hypertension heart group and diabetic cardiomyopathy group(P>0.05).Compared with the other groups,the IVS were significantly higher in hypertrophic cardiomyopathy group(P <0.05).3.Compared with control group,the Ss in each segment are significant decreased in the other three groups(P<0.05).There were no significant difference in Ss between hypertension heart group and diabetic cardiomyopathy group(P >0.05).Compared with other groups,the Ss in each segment are decreased in hypertrophic cardiomyopathy group(P < 0.05).4.In each group,the results had obtained good correlation between the LVEF and Ss(the Pearson correlations are 0.589,0.825,0.849,0.797).5.In control group,there is no significant correlation between the IVS and Ss.In hypertension heart group,hypertrophic cardiomyopathy group and diabetic cardiomyopath group,the results had obtained good correlation between the IVS and Ss,and there is a negative correlation between the two(the Pearson correlations are-0.731,-0.792,-0.538).Conclusion 1.Before the decline of globe left ventricular systolic function,myocardial strain have already decreased in patients with myocardial hypertrophy,which Suggested that STI can used to found in patients with early regional left ventricular function changes.2.In patients with myocardial hypertrophy,the Ss were positively correlated with LVEF,and were negatively correlated with IVS.3.To measuring the Ss by using 2D-STI,can make more understand of the changes in LV longitudinal motion and myocardial strain,and to evaluate global and regional myocardial funcation accurately and quantitatively in patients with myocardial hypertrophy.