Analysis Of The Clinical Characteristics Of Colorectal Adenoma In Xining Region

Objective: Collect the clinical data of colorectal adenoma in Xining Region,summary the the clinical,endoscopic and pathological features of the disease,which in order to accumulate some clinical data for the prevention and treatment of colorectal adenoma and colorectal cancer in Xining area.Methods:This is a retrospective review of all the clients who had colorectal adenoma diagnosed with concurrent endoscopic treatment at colonoscopy over a 5-year-long period spanning January 2011-December 2016 in Affiliated Hospital of Qinghai University,the Red Cross Hospital,Xining First People's Hospital,Xining Second People's Hospital.The aim of this study is to evaluate the patient's age,sex,race and the chief clinical information,endoscopic and pathological characteristics of colorectal adenoma.Results:(1)Data were obtained from a total of 576 patients,the M/F ratio was 1.87:1;Age between 21~84 years old,with an average age of 55.67±11.39;466 Han(80.9%),72 Tibetan(12.5%),other ethnic groups of 38 people(6.6%);the main symptoms were hematochezia in 172 cases(29.9%),followed by diarrhea in 137 cases(23.8%),abdominal pain in 111 cases(19.3%);(2)1392 adenomas were detected,he diameter is less than 1cm,accounting for 67.5%,with a single occurrence of 245(42.5%),and a total of 331(57.5%)patients,tubular adenoma is the most common pathological type,sites of the poly were most at the rectum and sigmoid colon;(3)The proportion of villous adenomasin diameter greater than 1cm was the highest,and there was a significant difference compared with other pathological types(P<0.01);(4)There was no significant difference in sex and age between the sites of adenoma growth(P>0.05);(5)The proportion of adenomas with diameter greater than 1cm was higher in the age group over 60 years old compared with other two age groups(P<0.01);(6)The proportion of female patients in middle and old age group was higher than that in young group(P<0.05);(7)There was difference in the proportionof adenomas among the young Tibetans among the other two groups(P<0.05);(8)The proportion of patients with tubular adenoma was the highest,and the proportion of patients with villous adenoma was the highest(P<0.01);(9)There was no significant difference in gender and the location of adenomas in different ethnic groups(P>0.05).Conclusion:(1)Most of the patients with colorectal adenoma in Xining area were in the elderly,and the majority of the patients were male.multiple is more common than single,with the increase of age,the proportion of female pati ents gradually increased,and the diameter is greater than 1cm;(2)Stool is the main symptom of colorectal adenoma and early warning;(3)The greater the diameter of adenoma,the higher the proportion of villous adenoma;(4)The predilection site of adenom a is the rectum and sigmoid colon,which is consistent with the epidemiological characteristics of colorectal cancer.