The Relationship Between Muscle Characteristics,Physical Performance And Osteoporosis In Tianjin Elderly People

Objective:The aim of the present study was 1)Assessment of the association of muscle strength and muscle mass with osteoporosis in an elderly Chinese suburb dwelling population;2)Determine the influence osteoporosis on muscle mass,muscle strength,and mobility over a 1-year period in an elderly Chinese suburban dwelling population.Methods:This cross-sectional study was conducted on 1,168 older participants aged ?60years from two suburban communities in Chadian and Hougu,Tianjin.Average was66.9�6.2 year(female: 652,male: 516).All subjects were invited to participate in our objective measurements and questionnaire survey.The objective measurements included height,weight,body composition,muscular strength,physical activity,etc.;questionnaire collected information included general population information(gender,age,pregnancies,level of education,nourishment state etc.)Social behavior characteristics(smoking history,drinking history,fall history,daily activity levels depressive tendencies,etc.)and medical history(hypertension,cardiovascular disease,osteoarticular,etc.)Physical performance-based assessments(time up and go test and4-m walk test).We measured at calcaneus by the quantitative ultrasound to defined osteoporosis,T value<-2.5 defined as osteoporosis.Associations between the muscle strength,muscle mass and physical performance with osteoporosis were explored through logistic regressionA year later,this cohort study was conducted on 632 suburb-dwelling participants in Chadian,Tianjin.We collected the relative information again,and investigate the incidence of osteoporosis in the elderly population of this region and determine the influence of osteoporosis on muscle mass,muscle strength,and mobility in older Chinese people.Results:In the cross-sectional study,the overall prevalence of sarcopenia was 61.6% inthis region.When age,gender,BMI,education level,history of diseases,history of smoking and drinking habits,physical activity(IPAQ),fat mass and history of falls were adjusted for,elderly people with a lower grip strength were significantly more likely to suffer from osteoporosis(P=0.023).There was no association between muscle mass and osteoporosis after adjustments of all covariates(P=0.205).Meanwhile,no association in time up and go(P=0.916)and 4-m walk test(P=0.325)with osteoporosis.A year later,this cohort study was conducted on 632 suburb-dwelling participants in Chadian,Tianjin.We found that the incidence of osteoporosis was(men: 47.8%;women: 70.8%).Grip strength in study participants with osteoporosis decreased rapidly over the course of the study(women: difference=-15.99%,P<0.001;men: difference=-11.50%,P<0.001).Only in women with osteoporosis,the 1-year decrease in grip strength was accompanied by significant deterioration in muscle mass(difference=-11.50%,P=0.037),even after adjusting for confounding factors.There was no significant reduction in 4-m walk test in participants with osteoporosis in both genders(Women: difference=-5.09%,P=0.616 Men: difference=-7.98%,P=0.180).Conclusions:Determine the association of muscle strength,muscle mass and physical performance has a certain value.In our study,we found muscle strength was negatively related to osteoporosis after adjusting for all other variable.In addition osteoporosis had a rapidly worse influence on muscle strength.This suggests that strength training in the early stages of osteoporosis may slow the onset of sarcopenia,reduce the likelihood of falls,and improve quality of life,reduce the financial burden on provide for the aged.