Study On Related Factors And Control Strategies Of Syphilis Mother To Child Transmission In Fujian

Objective This research is based on the situation of Fujian Province,maternal transmission of syphilis epidemic situation and analysis of related factors and adverse pregnancy outcomes and blocking effect,explore the problems and reasons in the spread of syphilis prevention and control work in our province at present,and puts forward the control strategy and corresponding policy suggestions,provide scientific basis for further promoting the comprehensive prevention and control carry out.Method In this study according to the Mother-to-child transmission of AIDS prevention,Syphilis and Hepatitis B management information system,the data of Fujian Provincial Maternity and Child Care Center and Fujian Provincial Center for Disease Control and Prevention,this study used the method of quantitative analysis and qualitative analysis.Selection of Fujian province in 2015 were 1068 cases of syphilis infection in pregnant women and neonates in 1082 cases(including 1054 cases of single fetal childbirth,14 cases of delivery of twins)as the research object,according to the pregnancy outcome of syphilis infection in pregnant women take a mismatched case-control study,a comprehensive analysis of the influence factors of perinatal transmission,with odds ratio(OR)and 95% confidence the interval(CI)associated with pregnancy outcome measure intensity of different influencing factors.In addition,through interviews to understand the health and family planning administrative departments responsible person and the relevant medical staff to prevent mother to child transmission of the views and suggestions.Enumeration data were used to describe the ratio and composition,and the chi square test was inferred.The mean,median and standard deviation of the measurement data were described,and the T test was used.Univariate analysis was statistically significant with multivariate unconditional Logistic regression analysis.All tests using double tail and P < 0.05 levels were statistically significant.Result(1)In 2004-2014,the incidence of syphilis increased year by year,the number of cases reported by men and women increased year by year,and the total number of men was slightly lower than that of women,but the gap between the two was narrowing.(2)During the period of 4 years in 2012-2015,the number of pregnant women in hospital delivery and the number of pregnant women with syphilis screen during pregnancy increased year by year,the number of syphilis infection and the infection rate showed an upward trend,but there were some differences in the infection rate of each district.(3)Univariate analysis showed that times of pregnancy,parity,the number of children,past diagnosis of syphilis infection,the diagnosis of syphilis infection period,gestational weeks of early detection,gestational weeks of delivery,drug use and drug treatment are risk factors of congenital syphilis;The factors affecting the occurrence of other adverse pregnancy outcomes were the number of pregnancy,past diagnosis of syphilis infection,the diagnosis of syphilis infection period,gestational weeks of early examination,gestational weeks of delivery,delivery mode,drug use and drug treatment.(4)Multivariate analysis showed that the prior diagnosis of syphilis infection,gestational weeks of delivery and the treatment of drug were closely related to congenital syphilis;The past diagnosis of syphilis infection and gestational weeks of delivery were closely related to other adverse pregnancy outcomes.(5)The public health significance of syphilis is seriously underestimated,and the government lacks sufficient attention;Syphilis mother to child transmission drugs blocking effect is good,but need to strengthen the use of supervision;Lack of awareness of individual medical institutions and medical staff,service awareness is not strong;Limited coverage of maternal and child blocking,intervention and follow-up work is difficult.Conclusion The project of preventing mother to child transmission of syphilis in Fujian has made some achievements since it was launched,but there are still some problems in the implementation of each district.Suggestions to improve theworking mechanism,strengthen guidance and support;Improve the overall level,improve service accessibility;Increase publicity potency dimension,regulate and guide public opinion;Strengthen tracking and follow up to ensure the effectiveness of intervene.