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Comparative Of Coronary Heart Disease Dectecting Coronary Arterial Calcification And Stenosis Between 16-MSCT And Coronary Angiography

Posted on:2009-06-18Degree:MasterType:Thesis
Country:ChinaCandidate:W M LiuFull Text:PDF
GTID:2144360245964918Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
Objective: coronary heart disease (CHD) is the pathophysiological basis of coronary stenosis caused by coronary atherosclerosis, coronary artery calcification (CAC) coronary sclerosis is a part of the process, reflecting the plaque load. The purpose of this study observed coronary CT angiography (CTA) and the selective coronary angiography (CAG) of the two methods of detection CAC, according to CTA plaque on the classification, comparison and non-calcified plaque calcification of the coronary artery lumen plaque narrow the impact of CTA in the maximum intensity projection (MIP) and / or reformation (MPR) image on the specific parameters and simply calcified plaque in coronary stenosis related to observe the shape of calcified plaques and the degree of stenosis ; CTA diagnosis of calcified plaque and non-calcified plaques and CAG consistency.Methods: Over the same period to 16 - MSCT examination of the CAG and 38 cases of patients with coronary heart disease and the clinical records of patients with coronary heart disease data analysis. The use of coronary angiography shares or radial artery intubation, MSCT coronary angiography and the results of the outcome of double-blind controlled study. Coronary vascular tree is divided into 12 paragraphs. CTA record results: calcification spots, calcified plaque pure and mixed plaque distribution; based on the evaluation of coronary artery calcification semi-quantitative methods, records show calcification of the CAG, according to CTA testing different components of plaque, plaque - Non-calcified plaque (soft patch and a non-calcified plaque consisting mainly of mixed plaque) and calcified plaque (simple calcified plaque and calcification mainly of mixed plaque) group. The degree of coronary artery stenosis is divided into significant (> 50 percent) and non-significant narrow (<50%); CTA in the MIP and MPR image reconstruction, simple observation of specific calcified plaque in diameter, the plaque in diameter and the corresponding normal Vascular diameter ratio, length, MIP images recorded on the simple calcified plaque size and shape. X 2 tests conducted with samples of the significant differences between the test, a test of the Kappa CAG CTA and consistency of the results, with Pearson's correlation and Spearman rank correlation analysis related to P <0.05 as a statistical test.Results: 1. Calcified plaque CTA detected: 38 cases of patients with CAC six cases, accounting for 15.8%, CAC32, accounting for 84.2 percent. 38 cases of patients with a total of 456 vessels of 30 found soft plaque, calcification spots 32, 78 simple calcified plaque, mixed calcified plaque 25. Calcified plaque before left descending nearly six (28/38, 73.7%)> Sec right coronary artery (15/38, 39.5%)> left circumflex near-paragraph(8/38,21.1%). 2. CTA to detect calcified plaque as a standard, Application X 2calcified plaque with the availability of diabetes, hypertension, hyperlipidemia, smoking and age, no significant difference (P values> 0.05). 3. CAG CTA and the detection of calcification have good correlation sexual. 4. Non-calcified coronary artery plaque Express Group and the Group calcified plaque in the luminal stenosis led to the probability of the difference was significant difference (X 2 = 8.188, p = 0.004), the soft plaque and consisting mainly of non-calcified plaque mixed is a significant lead vascular stenosis factors. 5. MPR image reconstruction, calcified plaque diameter and the diameter plaque / diameter ratio of normal coronary stenosis and no correlation in the MIP images, calcified plaque diameter and the diameter plaque / diameter ratio of normal correlated with coronary artery stenosis (0.01

50%) main reason, the analysis CTA mainly non-calcified lesions observed. 3. Coronary CTA observation of calcium plaque, mainly of mixed plaque, mixed plaque from coronary artery stenosis as the main reason for the more severe; simply calcified plaque from artery stenosis mostly mild to moderate. Image reconstruction in the MPR, the main observation of the composition of plaque in the MIP images calcified plaque in the observation simply Some of the specific parameters can be the reaction of coronary stenosis, but not the size of calcified plaque reaction coronary stenosis.

Keywords/Search Tags:multi-slice CT (MSCT), coronary CT angiography (CTA), coronary angiography (CAG), coronary artery calcification (CAC)
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