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Analysis On Imaging And Clinical Characteristics Of Pulmonary Tuberculosis Complicated With Diabetes Disease

Posted on:2018-10-21Degree:MasterType:Thesis
Country:ChinaCandidate:L LiuFull Text:PDF
GTID:2334330536469686Subject:Internal medicine
Abstract/Summary:PDF Full Text Request
ObjectiveTo analyze the imaging and clinical characteristics of pulmonary tuberculosis combined with diabetes mellitus(DM-PTB)and the prognosis of the patients after treatment,to increase the understanding and cognition of tuberculosis with diabetes and to improve the early diagnosis accuracy for PTB,predict the prognosis and guide clinical treatment.All the patients were diagnosed from the General Hospital of Ningxia Medical University between January 2013 and April 2016.MethodsSelected the clinical data of 52 patients with pulmonary tuberculosis and diabetes mellitus and 52 peer patients with simple pulmonary tuberculosis.as the observation group(DM-PTB group)and the control group(PTB group).All of the patients were diagnosed from the General Hospital of Ningxia Medical University between January 2013 and April 2016.Through analyze and summarize the clinical data of patients in both groups to explore the characteristics of pulmonary tuberculosis patients with diabetes compared to those with simple pulmonary tuberculosis in the pathogenesis,clinical symptoms,auxiliary examination,treatment and other aspects.ResultsIn the observation Group: it contains 32 male patients,20 female patients and patients over 60 years of age accounted for 32 cases(61.5%);including 35 patients who had diabetes mellitus earlier than phthisis(67.3%),20 patients with atypical tuberculosis poisoning symptoms(38.46%)and 38 patients with positive Mycobacterium tuberculosis(73.08%);9 patients whose focus was distributed in upper lobes(17.31%),18 patients with caseous necrosis(36.62%)and 21 patients who has formed cavity(40.38%).33 patients whose focus was widely distribute involving multiple lung lobes(63.46%);and 14 patients had a good blood glucose control and 2 patients had cavities(14.29%),38 patients had bad blood glucose control and 19 patients had cavities(50%);after two months of treatment,there are 46 patients in remission,with good glycemic control in 37 cases pulmonary tuberculosis disease had improved.In the control Group: it contains 35 male patients,16 female patients and 33 patients at the age of 60 and above(63.5%);including 5 patients with atypical tuberculosis poisoning symptoms(9.62%)and 27 patients with positive Mycobacterium tuberculosis(51.92%);2 patients whose focus was distributed in upper lobes(3.85%),6 patients with caseous necrosis(11.54%)and 9 patients who has formed cavity(17.31%);the focus types are located involving 29 patients with single lung slice(55.77%).After two months of treatment,52 patients all have different levels of remissions and absorptions in focus.Conclusions1.In DM-PTB Group,male and the elderly at the age of 45 and above are in major percent.Comparing with phthisis,more patients with diabetes mellitus were diagnosed.2.When the patients with phthisis have diabetes mellitus,they are always lack of typical poisoning symptoms of phthisis comparing with pure phthisis.There are no obvious clinical symptoms and physical signs.In addition,they always have a high rate TB positive rate of sputum smear and sputum culture.3.In DM-PTB Group,the iconography shows it has a wide scope of disease involving multiple lung lobes.While it has no dependency with positive TB bacteria,and the atypical focus always happens in the front of lung slice.Comparing with Control Group,Observation Group is easier to cause caseous lesions and cavities,and the walls of cavities are always thick.4.In Observation Group,The blood glucose conditions in vivo can take effect on the happening of cavity in lung.And the patients with better blood glucose control can always have an obvious lower occurrence rate of cavity.A high blood glucose level is bad for lesions absorption.After treatment,the patients with good blood glucose control always have a higher treatment rate.
Keywords/Search Tags:pulmonary tuberculosis, diabetes, imaging feature, clinical analysis
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