The Value Of Tp-e And Tp-e /QTc Ratios In The Prediction Of Ventricular Fibrillation In Patients With Acute ST-elevation Myocardial Infarction Of Tibetan And Han Nationality

Objective: To study the value of Tp-e and Tp-e / QTc estimating ventricular fibrillation in patients with STEMI in Han nationality,To study the value of Tp-e and Tp-e / QTc estimating ventricular fibrillation in patients with STEMI in Tibet nationality.Methods: 41 STEMI of Tibet nationality in our hospital from February,2014 to January 2017 were selected as the observation group and 32 healthy person of Tibet nationality with same age in the same period were selected as the control group.40 STEMI of Han nationality in our hospital from February,2014 to January 2017 were selected as the observation group and 25 healthy person of Han nationality with same age in the same period were selected as the control group.A 12-lead or 18-lead ECG was obtained for all the patients in the observation group in 10 minutes.Patients were observed in the intensive coronary care unit for at least first 48 hours and then in the step-down unit and be divided into ventricular fibrillation group and non-ventricular fibrillation group according to ventricular fibrillation.there are 5 in ventricular fibrillation group and 36 in non-ventricular fibrillation group in Tibet nationality,there are 6 in ventricular fibrillation group and 34 in non-ventricular fibrillation group in Han nationality.The Tp-e value and Tp-e/QTc ratio of observation group and control group in Tibet nationality were compared.The Tp-e value and Tp-e/QTc ratio of ventricular fibrillation group and non-ventricular fibrillation group in Tibet nationality were compared.The Tp-e value and Tp-e/QTc ratio of observation group and control group in Han nationality were compared.The Tp-e value and Tp-e/QTc ratio of ventricular fibrillation group and non-ventricular fibrillation group in Han nationality were compared.ROC curve was used to analyze the prediction value of Tp-e value and Tp-e/QTc ratio on ventricular fibrillation in STEMI in Tibet nationality.ROC curve was used to analyze the prediction value of Tp-e value and Tp-e/QTc ratio on ventricular fibrillation in STEMI in Han nationality.Results: 1.Compared with control group,the Tp-e value(113±21 vs 86±16)and Tp-e/QTc ratio(0.248±0.046 vs 0.199±0.040)of observation group was higher than control group and the difference was statistically significant in Tibet nationality(P<0.05).Compared with control group,the Tp-e value(100±20 vs 74±16)and Tp-e/QTc ratio(0.235±0.044 vs 0.196±0.039)of observation group was higher than control group and the difference was statistically significant in Han nationality(P<0.05).2.(1)Compared with non-ventricular fibrillation group in Tibet nationality,the Tp-e value(146±11 vs 108±18)and Tp-e/QTc ratio(0.313±0.019 vs 0.239±0.041)of ventricular fibrillation group in Tibet nationality was higher and the difference was statistically significant(P<0.05).(2)Compared with non-ventricular fibrillation group in Han nationality,the Tp-e value(130±13 vs 95±16)and Tp-e/QTc ratio(0.304±0.021 vs 0.222±0.034)of ventricular fibrillation group in Han nationality was higher and the difference was statistically significant(P<0.05).3.Area under the ROC curve results showed:(1)Area under the ROC curve(0.969),sensitivity(100.0%)and specificity(80.6%)of Tp-e value estimation ventricular fibrillation incidence of STEMI patients in Tibet nationality were high,which mean that prediction value of Tp-e value on ventricular fibrillation incidence of STEMI patients was good.Area under the ROC curve(0.950),sensitivity(100.0%)and specificity(88.9%)of Tp-e/QTc ratio estimation ventricular fibrillation incidence of STEMI patients in Tibet nationality were high,which mean that prediction value of Tp-e/QTc ratio on ventricular fibrillation incidence of STEMI patients was good.(2)Area under the ROC curve(0.971),sensitivity(100%)and specificity(88.2%)of Tp-e value estimation ventricular fibrillation incidence of STEMI patients in Han nationality were high,which mean that prediction value of Tp-e value on ventricular fibrillation incidence of STEMI patients was good.Area under the ROC curve(0.990),sensitivity(100%)and specificity(94.1%)of Tp-e/QTc ratio estimation ventricular fibrillation incidence of STEMI patients in Han nationality were high,which mean that prediction value of Tp-e/QTc ratio on ventricular fibrillation incidence of STEMI patients was good.Conclusion: Tp-e value and Tp-e/QTc ratio in STEMI patients in Tibet nationality were significantly elevated.Prediction value of Tp-e value and Tp-e/QTc ratio on ventricular fibrillation of STEMI patients were good in Tibet nationality.Tp-e value and Tp-e/QTc ratio in STEMI patients in Han nationality were significantly elevated.Prediction value of Tp-e value and Tp-e/QTc ratio on ventricular fibrillation of STEMI patients were good in Han nationality.