Investigation On The Correlation In Patients With Acute Hypertensive Intracerebral Hemorrhage Between The Volume Of Hematoma And Blood Pressure

Objective:To investigate the relationship between blood pressure and hematoma volume in patients with acute cerebral hemorrhage.And to provide some clinical evidence for early intervention of patients with cerebral hemorrhage.Methods:From January 2014 to August 2015,patients with hypertensive intracerebral hemorrhage were admitted to the emergency department of Shihezi People's hospital.1.In the emergency admission and within 6 hours?12-24 hours?48-72 hours,finished head CT(computed tomography,CT),calculated the volume of hematoma.According the calculation formula to define the volume of hematoma increased 33% as hematoma enlargement.2.Within 72 hours monitoring blood pressure value by admission bedside monitor.3.Calculated 6?24?72 hours systolic blood pressure(mean systolic blood pressure,MSBP)and diastolic blood pressure(mean diastolic blood pressure,MDBP.4.Correlation analysis between the volume change of hematoma and the indicators of blood pressure.Results:1.General data analysis:there was no significant difference in age,gender,onset time,GCS scores at admission,bleeding site and so on.2.Patients divided by hemotoma volume enlargement or not into 2 groups within 6 hours correlation analysis : 6 hours one group without hematoma expansion and the other group with hematoma enlargement,the MSBP were 155.98±18.27 mm Hg and 176.65 ± 28.44 mm Hg,t=-2.552,95%CI(-36.801,-4.547),p=0.013.6 hour hematoma without expansion group and hematoma expansion group,the MDBP were 90.68 ±10.38 mm Hg and 102.83±15.39 mm Hg,t=-2.657,95%CI(-21.248,-3.044),p=0.010.p<0.05,the difference was statistically significant.3.According to the average level of systolic blood pressure MSBP :(1)within 6 hours patients were divided into two groups: MSBP ?180mm Hg group and MSBP>180mm Hg group,the two groups on admission hematoma volume were 20.77±16.43 ml and 34.44 ±29.52ml;6 hours of admission showed hematoma volume integral were 22.18±18.19 ml and 40±33.31 ml.p<0.05,the difference was statistically significant.(2)within 24 hours patients were divided into two groups: MSBP ? 140 mm Hg group and MSBP>140mm Hg group,the two groups on admission hematoma volume were 16.97±14.13 ml and 25.51±20.30ml;24 hours of admission were hematoma volume were 17.10±13.35 ml and 26.12±20.30 ml.p<0.05,the difference was statistically significant.4.According to the overall average diastolic blood pressure MDBP: within 6 hours patients were divided into two groups: MDBP ? 110 mm Hg group and MDBP>110mm Hg group,the two groups on admission hematoma volume were 21.42±18.39 ml and 33.33± 19.41ml;6 hours of admission were hematoma volume were 22.80±19.86 ml and 41.33±27.89 ml.p<0.05,the difference was statistically significant.Conclusion:1.This study analyzed the hematoma enlargement and MSBP,MDBP within 6 hours has significant difference,suggesting that the hematoma enlargement may be related to the blood pressure level within 6 hours.6 hour systolic blood pressure controlling in less than 180 mm Hg,6 hour diastolic blood pressure controlled in less than 110 mm Hg and hematoma further changes have a correlation.2.This study suggested 24 hour systolic blood pressure controlling in less than 160 mm Hg,correlated with the volume of the hematoma further changed;blood pressure controlled is very important.3.This study suggested 72 hour diastolic blood pressure controlling in less than 90 mm Hg,correlated with the volume of the hematoma further changed;blood pressure controlled is very important.