The Characteristics Of Hypoglycemia Among Adult Hospitalized Patients With Type 2 Diabetes And Influence Factors Analysis

Objectives To explore the characteristics of hypoglycemia and related factors in adult hospitalized patients with type 2 diabetes,optimizing hospital blood glucose management and preventing hypoglycemia.Methods Select in October 2015 to October 2016 all adult hospitalized patients with type2 diabetes with 957 cases,including 476 cases of male,female 481 cases,age 28 ~ 84 years old in department of endocrinology affiliated hospital of the North China University of Science and Technology.Including hypoglycemia occurred during hospitalization for case group,a total of 152 cases;without the hypoglycemia as a control group,a total of805 cases.Patients in groups were regular monitored blood glucose including before meals,2 hours after meals and before going to sleep,compared two groups of age,sex,duration of diabetes,Hb A1 c,BMI,ALT,AST,TC,TG,HDL-C,LDL-C,Cr,UA,diabetes treatment and complications.All the data were analyzed by statistical software package SPSS 22.0.The normal distribution of the measure information were expressed as mean ±standard deviation(x ± s),between the two groups compared with independent samples ttest;count data as a percentage,with by chi-square test;the risk factors of hypoglycemia in adult hospitalized patients with type 2 diabetes with non conditional logistic regression model analysis.Test standard: P < 0.05,the difference was statistically significant.Results 1 Of 957 adult hospitalized patients with type 2 diabetes,152 cases developed hypoglycemia,the occurrence of hypoglycemia was 15.88%.The highest occurrence of hypoglycemia,before lunch followed by going to bed and before dinner.2 Between the two groups in sex,age,diabetes complications by chi-square test showed that the difference was not statistically significant(P > 0.05).Duration of diabetes,Hb A1 c,BMI,diabetes treatment by chi-square test showed that the difference was statistically significant(P <0.05).Between the two groups in ALT,AST,TC,TG,HDL-C,Cr,UA by t-test showed that the difference was not statistically significant(P > 0.05).LDL-C by t-test showed that the difference was statistically significant(P < 0.05).Taking all the indexes of statistical significance of the chi-square test and the t-test into the non conditional logistic regression model analysis,showed that risk factors of hypoglycemia of adult hospitalized patients with type 2 diabetes were duration of diabetes,lower BMI,lower Hb A1 c,the use of insulin therapy.Conclusions 1 The occurrence of hypoglycemia of adult hospitalized patients with type2 diabetes was 15.88%.During hospitalization,the highest rate of hypoglycemia was before lunch,and followed by before sleep and before dinner,suggesting that we had to strengthen glucose monitoring and prevention.2 Duration of diabetes,lower BMI,lower Hb A1 c,the use of insulin therapy was the risk factors of hypoglycemia of adult hospitalized patients with type 2 diabetes.The longer the duration of diabetes,the lower BMI,the lower Hb A1 c,the use of insulin therapy increased the risk of hypoglycemia.