Analysis Of Risk Factors And Prevention Of Anastomotic Leakage After Rectal Cancer Dixon Resection

Objective: To collect the surgericl cases of rectal cancer that meet the inclusion criteria and analysisthe history information of different patients,physical examination,laboratory test results,iconography examination,pathological report and so on.To analyze the risk factor of anastomostic leakage after operation and explore the prevention measuers,in order to give some reference for clinical work.Methods: Retrospective analyze the information of four hundred and twenty-eight patients with rectal cancer were admitted from January 2012 to December 2015 in The First Affiliated Hospital of Wannan Medical college.The relationship between the number of cases anastomostic leakage and genger,age,hypertension,diabetes,root resistance,preoperative albumin,hemoglobin level,Neoadjuvant chemoradiotherapy,anastomosis of the distance from the anal verge,operation method,operation time,TNM staging,lymph node metastasis by analyzed.single factor analyze with ?2 test and multi factor analyze with logistic regression test according to using spss17.0 software.Results: Among 428 rectal cancer with Dixon resction,there are 26 cases of anastomostic leakage after surgery,the incedent rate of anastomotic leakage is about 6.07%(26/428).The occurrence of anastomotic leakage was related to age,diabetes,preoperative albumin,distance of anastomotic from anal edge,operation metiod,tunor TNM staging(P<0.05).Meanwhile gender,preoperative hypertension,Body Mass Index(Body Mass Index,BMI),preoperative hemoglobin level,Neoadjuvant chemoradiotherapy,surgery time and lymphatic metastasis were not statistically significant(P > 0.05).Beacuse of too litter samples,some relavant factor such as preoperative neoadjuvant chemoradiation,body mass index(Body Mass,Index,BMI),whether preventive colostomy fail to be statistics.Conclusion: The occurrence of anastomotic leakage was related to age,diabetes,preoperative albumin,distance of anastomotic from anal edge,Neoadjuvant chemoradiotherapy,operation metiod,tunor TNM staging(P < 0.05),among them age,diabetes,preoperative albumin,distance of anastomotic from anal edge are independent risk factors of anastomotic leakage after rectal cancer dixon resection.For relevant risk factors,formulate reasonable treatment scheme,can effectively reduce the occurrence of postoperative anastomotic leakage.