Association Between Green Tea Intake And Atrial Fibrillation In A Chinese Population

Objective:The aim of the present study was to assess the association between green tea intake and incidence of atrial fibrillation(AF)in a Chinese population.Methods:In order to minimize the bias,subjects were random recruited as case group who diagnosed as atrial fibrillation,excluded the possibility of no reliable diagnosis of the disease and secondary atrial fibrillation patients,including valvular heart disease,cardiomyopathy,congenital heart disease,hyperthyroidism etc.All information of patients were collected in the heart department of Jiangsu Province People's Hospital from September 2014 to October 2015.A total of 801(mean age:62 years;56%male)subjects were enrolled:401 AF patients and 400 controls.All subjects completed a questionnaire and the associations between their green tea drinking habits and incidence of AF were assessed using the odds ratio(OR)and binary logistic regression.Than the associations between the frequency,concentration,time of green tea drinking and incidence of AF were assessed using the odds ratio(OR)and trend analysis.The relationship between green tea intake and incidence of different types of AF were evaluated using the odds ratio(OR)and trend analysis.Results:After multivariate adjustment,green tea intake presented as a protective factor against the incidence of AF(OR:0.349,95%CI:0.253-0.483,P<0.001).The green tea protection was showed downward trend with increasing green tea intake(P for the trend= 0.001).Low frequency,low concentration,short-term tea consumption was classified as low-dose green tea intake.Green tea intake decreased the incidence of both paroxysmal AF(OR:0.307,95%Cl:0.216-0.436,P<0.001)and persistent AF(OR:0.355,95%Cl:0.261-0.482,P<0.001)and may be associated with a decreased incidence of AF.Conclusion:This study suggests that low-dose green tea intake strongly protects against AF.