Clinical Application Of High Resonlution Magnetic Resonance Imaging In Middle Cerebral Arteries Ischemic Stroke

Objective:In this study,the atherosclerosis patients with ischemic stroke underwent HRMRI with 3.0T scanner.To analyze and compare stenosis rate ? plaque burden ? Intraplaque hemorrhage ? vascular remodeling ? plaque location between both MCA of each patient and explore the risk factors for ischemic stroke in ICAD patients.Methods:The patients enderwent HRMRI examination who began with ischemic stroke within 72 hours and people with diagnosis of MCA infarction was chosen form them.vascular area(VA),lumen area(LA)was Measured at the maximal lumen narrowing sites and reference sites.Wall area(WA)?Plaque area(PA)? Percent plaque burden ?narrow rate and remodeling index was calculated and the characteristic of plaque distribution and intraplaque hemorrhage was assessed.The resultsThe comparison was make about both side MCA of the patients with ischemic stroke.Differences of the vascular area(VA)had no statistical significance(p> 0.05);The narrowest level lumen area(LA)of stroke side is less than the contralateral.The difference was statistically significant(p< 0.05);the wall area(WA),plaque area(PA),plaqueburden and the stenosis rate of stroke side is greater than the contralateral side,the difference was statistically significant(p<0.05).On the stroke side,MCA had positive remodeling of 26 cases(44.8%),no obvious remodeling 0f 19 cases(32.8%),negative remodeling of 13 cases(22.4%).on the contralateral side,MCA happen positive reconstruction of 11 cases(19.0%),no obvious refactoring of 39cases(67.2%),negative refactoring of 8 cases(13.8%).On both sides the proportion of MCA reconstruction is different(?2 = 14.166,P < 0.05),and positive remodeling of stroke side is greater than the contralateral side.Side of stroke: 14 cases(24.1%)plaques were located at the superior wall,15 cases(25.9%)at the inferior wall,17 cases(29.3%)at the ventral wall,12 cases(20.7%)at the dorsal side.In the contralateral stroke side : 6 cases(10.3%)at the superior wall,24 cases(41.4%)at the inferior wall,23 cases(39.7%)at the ventral wall,5 cases(8.6%)at the dorsal side.on the both side,the plaque at inferior and ventral wall were more than that at the superior and dorsal wall and at the superior and dorsal wall the plaque of the infarction side were more than that of the contralateral side.The difference was statistically significant(?2=8.929,p< 0.05).on the infarction side 16(27.6%)cases had IPH;on the other Side 3(5.1%)cases with intraplaque hemorrhage.On both sides the MCA had the different proportion of intraplaque hemorrhage(?2=10.637,p< 0.05).The logistic regression analysis showed that stenosis rate,positive remodeling,superior and dorsal located plaque,plaque hemorrhage was ischemic stroke risk factors for atherosclerosis patients.Conclusion1.Plaque load was associated with ischemic stroke;stenosis rate?vascular positive remodeling ? plaque distribution in the upper vesselwall and Intraplaque hemorrhage is a risk factor for ischemic stroke;2.Doctor can more accurately evaluate atherosclerotic vascular status and predict risk of infarction by HRMRI technology.