The Clinical Efficacy Study Of Self-Made Anshen Mixture In Treating Insomnia Of Liver-Qi Stagnation Syndrome

Research purposes:Collecting the clinical data of patients with liver-qi stagnation,and using a self-controlled study to preliminary investigate the efficacy of self-made Anshen mixture in treating liver-qi stagnation syndrome of primary insomnia,to provide guidance for its clinical application.Research methods:By using the self-controlled design.Selecting the liver qi stagnation patients with insomnia from the patients treated in the Jiangsu Province,Chinese medicine hospital encephalopathy center from March 2016 to February 2017 who conforming to this test inclusion standard,and give them the treatment after fully informed consent to Anshen mixture.The researcher evaluates the Pittsburgh Sleep Quality Index,the TCM Syndrome Classification Scale and Quantitative Integration of Liver-qi Stagnation Syndrome in the 0,14 and 28 day respectively.Then the researcher analyzes the data by using the SPSS21.0,and compares the differences between the efficacy standards before and after treatment.Results:53 patients were enrolled in this study,from which 5 patients were lost,and only the data of 48 patients were statistically analyzed,which showing that compared with the 0 day,the Pittsburgh Sleep Quality Index,the TCM Syndrome Classification Scale and Quantitative Integration of Liver-qi Stagnation Syndrome were improved obviously in 14 and 28 day,and the difference was statistically significant(P<0.05).Conclusions:This study shows that self-made Anshen mixture has a good effect on the treatment of primary insomnia,liver qi stagnation syndrome.However,there are some limitations in this study,further randomized,double-blind,large-scale,multi-center studies are needed to further prove its efficacy and provide a more reliable basis for its clinical application.