The Correlation Study Of Left Ventricular Systolic Function Calculated By Automated Cardiac Motion Quantification

Objective:To explore the correlation of left ventricular systolic function calculated by automated cardiac motion quantification(aCMQ)and three-dimensional quantitative analysis(3DQA).Methods:According to LVEF by 3DQA,patients were divided into abnormal cardiac function group(LVEF<50%)and normal cardiac function group(LVEF?50%).Dynamic images from two chamber view(AP2),four chamber view(AP4)and three chamber view(AP3)of left ventricular long axis were acquired from 32 patients with abnormal cardiac function and 119 normal subjects.AP2 longitudinal strain(AP2LS),AP4 longitudinal strain(AP4LS)and AP3 longitudinal strain(AP3LS)as well as the left ventricular global longitudinal strain(LVGLS)were measured by aCMQ.While left ventricular end diastolic volume(LVEDV),left ventricular end systolic volume(LVESV)and LVEF were derived through aCMQ automatically calculated region of interest(ROI)driven automation.Left ventricular systolic function indexes obtained by aCMQ and 3DQA were correlated.Results:No significant differences were found between the two groups in gender,body mass index(BMI)and age(P>0.05).LVEF of abnormal group by 3QDA and aCMQ were much lower than normal group(P<0.01).The absolute values of AP2LS,AP4LS,AP3LS and LVGLS in abnormal groupwere significantly lower than normal group(P<0.01).LVEF by aCMQ in abnormal group were positively correlated with LVEF by 3QDA methods(r=0.91,P<0.01);LVEF by aCMQ in normal group were positively correlated with LVEF by 3QDA(r=0.73,P<0.01).The left ventricular global longitudinal strain(LVGLS)were measured by aCMQ were negatively correlated with LVEF by 3QDA(r=-0.815,P<0.01).LVEF measured by aCMQ and 3DQA showed high inter-observer and intra-observer agreements in Bland-Altman charts.Conclusions:aCMQ has preferable repeatability.Comparing with the traditional measurement method,LVEF measured by aCMQ has higher correlation with that measured by 3QDA.aCMQ can be a new and relatively accurate method to evaluate the left ventricular systolic function.