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Clinical Analysis Of 31 Cases Of Epithelioid Sarcoma

Posted on:2018-03-15Degree:MasterType:Thesis
Country:ChinaCandidate:L DongFull Text:PDF
GTID:2334330515486677Subject:Surgery
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Objective: The clinical data of 31 cases of epithelioid sarcoma treated by Tumor Hospital Affiliated to Xinjiang Medical University were collected,analysis of epithelioid sarcoma(ES)factors affecting the clinical characteristics,treatment and prognosis,and provide the basis for clinical diagnosis and treatment.Method:The patients admitted in our hospital from January 2010 to December 2015 to and follow-up of 31 cases of epitheliod sarcoma clinical data were retrospectively analyzed and survival analysis and summarized the clinical features.Preoperative diagnosis,and postoperative recurrence of relevant data,with gender,age,tumor type,tumor size,chemoradiotherapy factors and recurrence factors.Results:In this group,6 patients died,the 5 year overall survival rate was 78.8%.All 31 cases were followed between 3 to 56 months.The median time was 27 months.Five year recurrence rate was 70.9%.In the single factor analysis,the impact of 5 year recurrence rates of factors for tumor type and tumor size.The tumors were more than 5cm and less than or equal to 5cm compared,tumor of the proximal and distal compared,the preceding 5 year recurrence rate was greater than in the latter(p < 0.05).In the control group,the explicit expression of CD34 was 90.3%,and the expression of INI1 was 83.9%.For the patients with tumor and peripheral vascular nerve boundary were not sharp,we provided preoperative radiotherapy after surgical treatment to avoid amputation.Conclusions: Epithelial sarcoma requires clinical,imaging,pathology combined,a clear diagnosis and differential diagnosis,extensive resection is still the main way of treatment.The lack of expression of INI1 can help the diagnosis and differential diagnosis of ES,but can not suggest the prognosis,and tumor size and tumor type and prognosis.Preoperative adjusted intensity of radiotherapy can shrink ES tumor size,in patients with locally advanced,can avoid the inconvenience caused by amputation,improve patient rate of return.
Keywords/Search Tags:Epithelioid sarcoma, Diagnosis, Treatment, Prognosis
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