| Objective:Retrospectively analysing the clinical and pathological data of the papillary serous adenocarcinoma of the uterine cervix(PSCC),such as its clinical features,pathological characteristics,diagnosis,treatment plan,prognosis.Method:Five cases of cervical serous carcinoma were found from cervical malignant tumor patients who were diagnosed firstly in the First Affiliated Hospital of Dalian Medical University and the Dalian Maternal and child health care hospital from Jan.1990-Jan.2017 and maked a retrospective analysis.Reslut:(1)The median age of the five patients was 44 years(41-64years).(2)Clinical manifestation:abnomal vaginal or contact bleeding three cases(3/5),abdominal discomfort one cases(1/5),no abnormality one cases(1/5).(3)Pelvic examination:polypoid or exophytic cerxical mass three cases(3/5),ulcerated or erosive hyperplasia 2 cases(2/5).(4)Stage according to 2009 FIGO:Ib1 three cases and Ib2 two cases.(4)Treatment plan:radical hysterectomy three cases,simple hysterectomy two cases.Neoadjuvant or postoperative chemotherapy two cases and postoperative radiotherapy one case.(6)Invasion and metastasis:Ibl five cases,except one for no lymph node dissection,deep cervical stromal invasion(>1/2)100%,lymph-vascular space invasion 100%,pelvic lymph node metastasis 100%which combined with celiac lymph node metastasis 40%.(7)Follow-up:follow-up information was available in 3 of 5 cases.The duration of follow-up was from 5 to 31 months.One died of extensive metastases within nine months of diagnosis,one was experienced tumor recurrence with 2 years after diagnosis.One was alive without evidence of recurrence or metastasis with 5 months of diagnosis.Conclusion:PSCC is a very rare and aggressive variant of cervical adenocarcinoma.The clinical characteristics were similar with common cervical cancer and cervical adenocarcinoma and sensitive to chemotherapy.The most important and earliest metastatic route of PSCC may be lymph node. |
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