| [Objective]:The patients with acupuncture on the treatment of osteoporosis,the bone mineral density and bone metabolism changes and pain,quality of life and the improvement of TCM,to explore whether acupuncture can produce that effect on the treatment of osteoporosis,as the scientific basis for therapy.[Method]:Randomized controlled study was adopted and the program was approved by the ethics committee.60 subjects who met the inclusion criteria and signed informed consent were recruited.According to the random number into the group,set up the test and blank treatment control,the experimental group was treated with Caltrate D600mg/,according to supplement the kidney acupoint acupuncture treatment,control group was given oral Caltrate D600mg/d.The test period is 3 months.The observation indexes include:Determination of X-ray absorptiometry and serum markers of bone metabolism in PINP\CTX\OP dual energy(before and after test);visual pain scores,life quality scores and TCM symptoms score(before and in the test every 1,2,3 month).[Conclusion]:In this study,60 postmenopausal women with osteoporosis were enrolled in the study.48 patients completed the trial.Among them,there were 23 cases in acupuncture group and 25 cases in control group.5 cases were excluded from the inclusion criteria and 7 cases were not treated.There was no significant difference in baseline values between the two groups before treatment.By means of normality test,t test and nonparametric test were used to drawconclusions after treatment:Statistical data analysis,1,bone mineral density of lumbar spine and femoral neck BMD and hip bone mineral density,bone mineral density of lumbar vertebra acupuncture group after treatment was 0.88590 + 10920,the control group after treatment was 0.8754 + 0.22384;femoral neck BMD acupuncture group after treatment was 0.7413 + 0.09068,the control group after treatment was 0.7612 + 0.09043;total hip the density of acupuncture group after treatment was 0.7921 +0.07705,the control group after treatment was 0.8096 + 0.09850.The results showed that there was no significant difference in bone mineral density between the acupuncture group and the control group after treatment(P>0.05)in the two groups.2,bone metabolism index,PINP acupuncture group after treatment was 52.2146 +19.45078,52.7904 + 23.15097 in the control group after treatment;CTX acupuncture group after treatment was 458.5417 + 201.57402,the control group after treatment was 457.2083 +211.93415;OC acupuncture group after treatment was 20.4992 + 5.17352,the control group after treatment was 20.9108 + 7.71508.Through the normality test,the t test was used to analyze the data of PINP,CTX and OP.The results showed that there were no statistically significant differences between the two groups after the treatment,the acupuncture group and the control group(P>0.05).3,January after treatment acupuncture group pain score was 5.1667 + 0.70196,the control group score was 5.7917 + 0.72106;February after treatment acupuncture group pain score was 4.7083 + 0.55003,the control group score was 5.7083 + 0.85867;March after treatment acupuncture group pain score was 4.2917 + 0.55003,the control group score was 5.6250 +0.85867;after repeated measurement analysis of variance test,the two groups were compared after treatment VAS score than the previous month were improved(F=26.788,P=0,000<0.05),acupuncture group and control group after treatment time each month,the comparison between the two groups VAS scores had significant difference(F=18.252,P=0.000<0.05).The acupuncture group is superior to the control group.4,January after treatment acupuncture group total body health measurement score was 44.7500 + 5.73509,the control group score was 44.3750 + 5.24042;acupuncture group after treatment in February physical health measurement score was 48.1667 + 7.53927,the control group score was 44.3750 + 5.31183;acupuncture group after treatment in March physical health measurement score was 58.4583 + 10.99399,control group score was 47.5000 + 5.80105;after repeated measurement analysis of variance test,results showed that acupuncture group and control group after treatment PCS each month compared were different,the PCS score after treatment were better than the previous month(F=52.159 P= 0.000<0.05).The PCS scores between the two groups were statistically significant(F=4.072,P=0.049<0.05).The acupuncture group is superior to the control group.5,January after treatment acupuncture group mental health measuring total score was 63.7083 + 7.07709,the control group score was 60.5417 + 7.07709;acupuncture group mental health treatment in February after the total measurement score was 66.7083 + 6.36894,the control group score was 60.4583 + 7.26504;acupuncture group mental health treatment in March after the total measurement score was 70.4583 + 5.91960,control group score was 60.7083 +6.60355;after repeated measurement analysis of variance test,results showed that acupuncture group and control group after treatment MCS each month compared were different,the MCS score after treatment were better than the previous month(F=54.506,P= 0.000<0.05),acupuncture group and control group after treatment time each month of the found MCS scores between the two groups had significant difference(F=8.993,P=0.004<0.05).The acupuncture group is superior to the control group.6,January after treatment acupuncture group of TCM syndrome score was 5.3333 +0.96309,the control group score was 5.1667 + 0.96309;acupuncture and TCM syndrome treatment group in February after the score was 4.7917 + 0.72106,the control group score was 5.5417 + 0.88363;acupuncture and TCM syndrome treatment group in March after the score was 4.2500 + 0.94409,the control group score 5.4167 + 0.97431;after repeated measurement analysis of variance test,results showed that acupuncture group and control group were compared in different TCM syndrome score each month after treatment,after treatment of TCM syndrome score were better than the previous month(F=25.379,P=0.000<0.05).After comparing the time of each month in the acupuncture group and the control group,it was found that there were differences in the scores of TCM syndromes between the two groups(F=3.250,p=0.048<0.05).The acupuncture group is superior to the control group.[Conclusion]acupuncture treatment can better improve the pain symptoms and improve the quality of life of patients,and can be used as the basic treatment choice for patients with osteoporosis.The mechanism of action remains to be further studied.This study reflects the BMD\PINP\CTX\OP value was no significant difference before and after treatment,on the one hand and the test cycle is short,still can not produce the quality of bone imaging changes;on the other hand,osteoporosis metabolism can be high conversion type,can also be a low conversion type,this study failed to refine grouping,and therefore can not be accurate the test results reflect.This also needs further study. |
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