| ObjectiveThe aim of this study was to investigate the clinical efficacy of Erigeron injection acupoint injection(Zusanli,Quchi)combined with traditional Chinese medicine(Four Jun four inverse Chinese medicine compound group)on functional dyspepsia postprandial distress syndrome(postprandial distress,syndrome,PDS)of liver depression and spleen deficiency.Through the main,objective observation indicators,Comprehensive evaluation of the western medicine group,traditional Chinese medicine compound group,acupoint injection combined with traditional Chinese medicine compound group in improving the clinical symptoms of PDS,safety and recurrence rate and the improvement of the quality of life of patients with differences,give full play to the advantages of traditional Chinese medicine.MethodsThis research adopts the prospective randomized controlled study meth od,according to the patient’s turn into the group,control group,experim ental group 1 and 2,collected a total of 115 FD patients in TCM Hospital of Guangzhou city in February 2016-2017 year in February the spleen and stomach out-patient standard test cases with the control group,a total of 35 cases,male 17 cases,female 18 cases,the experimental group of 2 a total of 36 cases,male 17 cases,female 19 cases;in the experimental group 1 consisted of 44 cases,male 17 cases,female 27 cases.In the cou rse of the study,the experimental group 1 and 2 were off 3 cases,contro 1 group 2 cases of loss,finally,There were 41 cases of experimental group1,a total of 33 cases in the experimental group 2 and the control group.The control group was given mosapride dispersible tablets 5mg/everytime,3 times/day,30min before meal orally,for 4 weeks;the experimental gro up 2 to four Jun four inverse compound Chinese medicine(dangshen 20g,Atr actylodesl5g,Poria 15g,bupleurum 6g,Fructus 10g,Radix Paeoniae Alba 1 Og,licorice 6g,endothelium corneum 15g,Salvia miltiorrhiza 10g,Datepl um persimmon 15g,Achyranthes 15g).The experimental group 1 on the basis of the experimental group 2 plus acupoint injection of Erigeron Injection(Zusanli,Quchi),Traditional Chinese medicine compound was a daily dose,divided into two times in the early,after lunch 2h,for a total of 4 wee ks.All patients were taking medicine in our hospital pharmacy.The clinica 1 symptomswere observed and compared with the patients after 1 week,2 we eks,3 weeks,4 weeks and 1 month after treatment.Results(1).Baseline data of two groups of patients before treatment(age,gender,duration)and total symptom score before treatment compared,d ifferences were not statistically significant,comparable(P>0.05).(2).experimental group 1:23 cases were cured,18 cases markedly e ffective 0 cases,invalid 0 cases,3 cases of loss,the total efficien cy was 100%,the cure rate was 56.10%;in the experimental group 2:1 cases were cured,26 cases markedly effective 5 cases,invalid 1 cases,3 cases were lost and the total efficiency 96.97%,the cure rate was 3.03%;control group:0 cases were cured,10 cases markedly effective 19 cases,invalid 4 cases,2 cases of loss,the total efficiency was 87.88%,the cure rate was 0%;three groups of patients after treatment,ov erall curative effect and total effective rate were not all the same(P<0.05);experimental group 1 and 2 with the control group there was significant difference between the two groups(P<0.01).The total effi ciency of three groups were compared between the experimental group an d the experimental group 1,2 compared with no significant difference(P>0.05),1 in experimental group compared with the control group ther e were significant differences(P<0.05),2 in experimental group compa red with the control group no significant difference(P>0.05).(3).Three groups of patients in the treatment of 1 weeks,2 weeks,3 weeks,4 weeks,the total score of the withdrawal 1 months after t he clinical symptoms,the comprehensive curative effect comparison,th e differences were statistically significant(P<0.05).(4).Three groups were treated for 1 weeks,2 weeks,3 weeks,4 wee ks,the total score of the withdrawal 1 months after the clinical sym ptoms are not all the same(P<0.05),a further 22 comparison suggests:after 1 weeks of treatment,the experimental group 1 and experimental group 2,experimental group 1 and control group showed statistical dif ferences(P<0.01)comments 2,the experimental group and the control g roup no statistically significant difference was found(P>0.05);for 2 weeks,3 weeks,4 weeks after the 1 months withdrawal,experimental g roup 1 and experimental group 2,experimental group 1 and control grou p,experimental group 2 and control group.The differences were statis tically significant(P<0.01).(5).Three groups were treated for 1 weeks,2 weeks,3 weeks,4 wee ks,the overall effect of withdrawal after 1 months are not all the sa me(P<0.05),further 22 tips:2 weeks of treatment,the experimental g roup after 3 weeks and 1 experimental group 2,experimental group 1 co mpared with the control group,the difference was statistically signif icant(P<0.01),2 in experimental group compared with the control grou p had no statistical significance(P>0.05);for 1 weeks,4 weeks,the experimental group discontinued after January 1 and 2 in the experimen tal group compared with control group,the difference was statisticall y significant(P<0.05).(6).Three groups of patients before and after treatment for 1 week s,2 weeks,3 weeks,4 weeks after drug withdrawal 1 months after the total score of clinical symptoms were compared,the differences had st atistical significance(P<0.05).The three groups were treated for 2 w eeks,3 weeks,4 weeks after treatment discontinuation,January with a total score of 1 weeks after the symptoms were compared,the differenc es had statistical significance(P<0.05),Three groups were treated fo r 3 weeks and 4 weeks after drug withdrawal after January and 2 weeks after treatment were compared,the differences had statistical signifi cance(P<0.05).The three groups after 4 weeks and 3 weeks after treat ment were compared,the differences had statistical significance(P<0.05);withdrawal after January and after 3 weeks of treatment compared.The experimental group 1,experimental group 2 had significant differe nce(P<0.01);the control group had no significant difference(P>0.05);withdrawal after January and after 4 weeks of treatment,there were no statistically significant difference(P>0.05).(7).Three groups of patients after treatment compared the recurren ce rate of withdrawal after 1 months was 22,a further comparison,the experimental group 1 and experimental group 2 and control group with t he control group,the recurrence rate was statistically significant(P<0.01),while the experimental group 1 and experimental group 2 recurr ence rate is statistically significant meaning(P>0.05).(8).The experimental group 2 in improving TCM individual symptoms such as discomfort,postprandial belching,irritable,insomnia and oth er symptoms of the effect is more significant than the experimental gr oup 1 and control group.ConclusionThrough clinical research have shown that:the experimental group and the control group can improve liver stagnation and spleen deficiency type of functional dyspepsia postprandial discomfort of clinical symptoms,but the experimental group in 1 compound Chinese medicine group plus acupoint injection,improve the clinical symptoms and the effect of the overall effect has more advantages,and reduce the recurrence rate,there were no obvious adverse reactions. |
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