| ObjectiveTo explore the correlation between TCM syndromes of nonvalvular atria 1 fibrillation(NAF)and CHA2DS2-VASc score.MethodsAll NAF patients entering hospital heart center of guangdong province from December 1,2014 to December 30,2016 were retrospectively reviewed.A ccording to hospital records to collect the patient’s age,gender,basic di seases,the CHA2DS2-VASc score and the patient’s symptoms,tongue and pulse condition of TCM.Undering the guidance of two experience of attending a nd above the doctor of TCM,and refering to the internal medicine of TCM a bout heart palpitations of TCM syndrome,the TCM syndrome types of NAF can be divided into Guilty timid syndrome(GTS),Blood deficiency syndrome(BD S),Drink water ling heart card(DWLH),Weak heart Yang syndrome(WHYS),Stasi s resistance heart arteries and veins(SRAV),The phlegm fire interference proof(PFIP)and Yin fire certificate(YFC).Analysising the relationship be tween the type of NAF and gender,age,and mergering disease;Analysising th e relationship between the syndrome types of TCM of NAF and gender,age,an d mergering disease;Analysising the relationship between the type of NAF and the syndrome types of TCM of NAF;Analysising the relationship between the syndrome types of TCM of NAF and the risk stratification of CHA2DS2-VASc score.Statistical packages SPSS20.0 are used for date analysis;Measu rement data uses mean±standard deviation or median(four digits),count d ata expressed in frequency;Measurement data meeting the needs of normal a nd homogeneity uses single factor analysis of variance between groups,the others use nonparametric rank and inspection;Count data mainly adopts th e χ2 test or Fisher exact probability method;The data statistics has signi ficance difference(P<0.05).ResultsThree hundred and eighty-six patients were enrolled.Including 121(31.4%)cases of paroxysmal AF,141(36.5%)cases of persistent AF,124(32.1%)c ases of permanent AF;197(51%)cases of female,189(49%)cases of male;aged 27-91,the average age(66.57 + 10.89).The types of TCM include 52(13.4%)cases of GTS,79(20.5%)cases of BDS,31(8.0%)cases of WHYS,23(6.0%)cases of DWLH,114(29.5%)cases of SRAV,50(13.0%)cases of PFIP,37(9.6%)cases of YFC;The minimum CHA2DS2-VASc score is zero points,the bigges t seven points;CHA2DS2-VASc score points grouped low latent danger in 49(12.7)cases,125(32.4%)cases of middle risk,212(54.9%)cases of hi gh risk.Chi-square found that there was no statistically significant differen ce between NAF and gender,merging disease;By using nonparametric rank and inspection analysis found that the age of different types of NAF patient was statistically significant(P<0.05),two comparison results show that t he age of permanent AF patient(73.56 + 8.54)was obviously higher than th at of paroxysmal AF patients’(62.83 + 12.25)year,and persistent AF group(63.62 + 8.32)years of age.Chi-square test or Fisher,s exact probability method show that the di stribution of syndrome type of TCM of difference types of NAF was statist ically significant(P<0.05),the percentage of syndrome typ of TCM sorting:SRAV(29.5%)、BDS(20.5%)、GTS(13.4%)、PFIP(13.0%)、YFS(9.6%)、WHYS(8.0%)、WDLH(6.0%);The different between syndrome types of TCM and gender has no statistical significance;The distribution of syndrome type of TCM of diff erence types of NAF between merging disease about heart failure,hypertens ion,diabetes,stroke/TIA/thromboembolism,vascular disease has statisticall y significant(P<0.05),the NAF patients merging heart failure were more t o see WHYS and WDLH,merging hypertension were more to see SRAV and PFIP,m erging diabetes were more to see SRAV,PFIP and YFS,merging stroke/TIA/thr omboembolism were more to see SRAV and PFIP,merging vascular disease were more to see SRAV.The nonparametric test methods shew that the average ag e of NAF patients between syndrome type of TCM was statistically signific ant,two comparison results shew that the average age of patient with WDLH(71.61±11.50)years,and SRAV(68.97±10.46)years is significantly higher than patients with YFS(64.35±8.60)yeas and BDS(63.72±8.97)years.Chi-square found that the distribution of syndrome types of TCM in di fferent types of NAF was statistically significant(P<0.05),the patients w ith paroxysmal AF was more to see BDS,GTS,SRAV and PFIP,the patients with persistent af was more to see SRAV,BDS,GTS and YFS,permanent AF was more to see SRAV,BDS,WHYS and PFIP.Nonparametric rank and inspection found that the risk stratification of CHA2DS2-VASc score between different syndrome types of TCM was statist ically significant(P<0.05).The type about GTS,BDS,WHYS,YFS was more to se e in the intermediate risk category,The type about SRAV,PFIP,WDLH was mor e to see in high-risk groups and the low-risk groups was more to see GTS and BDS.Nonparametric rank and inspection found that CHA2DS2-VASc score betwe en different syndrome types of TCM was statistically significant(P<0.05),comparing each others,the results showed that the CHA2DS2-VASc score of p atiente with SRAV,WDLH and PFIP is higher than other kind of syndrome typ es of TCM,and has a relatively high risk of thromboembolism.ConclusionThe type about GTS,BDS,WHYS,YFS was more to see in the intermediate r isk category,The type about SRAV,PFIP,WDLH was more to see in high-risk g roups and and the low-risk groups was more to see GTS and BDS.syndrome types of TCM can predict risk of ischemic stroke,the patient s with SRAV,WDLH,PFIP were relatively high risk of stroke. |
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