Clinical Observation On The Short-term Efficacy Of Side Effects After Radiotherapy For Nasopharyngeal Carcinoma Treated By Qingrejiedu And Yiqiyangyin

ObjectiveTo observe the clinical efficacy of the use of Qingrejiedu and Yiqiya ngyin method to prevent the recent side effects of radiotherapy in nasoph aryngeal carcinoma.To compare the data of the treatment group and the ob servation group,to evaluate the effect of Qingrejiedu and Yiqiyangyin on the prevention and treatment of nasopharyngeal carcinoma radiotherapy Cl inical value.MethodsA total of 25 patients with nasopharyngeal carcinoma were randomly di vided into treatment group and control group.Each group was treated with 25 cases.The treatment group was treated with Qingrejiedu and Yiqiyangy in Chinese medicine during radiotherapy.The scores of KPS score,classif ication and time of acute radiation oropharyngeal mucosal injury,the cla ssification and time of acute radioactive skin reaction and the classific ation of acute radiation salivary injury,the difference of quality of li fe after radiotherapy,and contrast the adverse reaction were recorded.ResultsThere was no statistically significant difference between the treatme nt group and the control group in the grade 1 and grade 2 acute oropharyn geal mucosa responses(P>0.05).The incidence of grade 3 acute oropharyng eal mucosal response in the treatment group was significantly lower than that in the control group(P<0.05),Suggesting that the treatment group h as a significant advantage in reducing severe acute oropharyngeal mucosa responses.In acute radioactive skin reaction time,classification and treatment group in grade 1 acute radioactive skin reaction time later than the con trol group on average,the difference statistically significant(P<0.05);T reatment group grade 2 of acute radioactive skin reaction rate lower than the observation group,the difference statistically significant(P<0.05);Treatment group grade 3 of incidence of acute radiation skin reactions co mpared with control group,the difference has no statistical significance(P>0.05).In terms of acute radioactive salivary gland damage degree,into the g roup of patients with salivary gland were concentrated in grade 1 to grad e 3.The treatment group and control group in different degree of radioact ive incidence of salivary gland damage degree,statistically significant difference(P<0.05);Salivary gland damage at level 3 of the incidence of treatment group was 0%,the incidence of the control group was 12%,sugge sts that the treatment group can reduce the incidence of salivary gland d amage serious level.In terms of survival after radiotherapy quality comparison between th e two groups of patients after radiotherapy have varying degrees of sore throat,dry mouth,phlegm.Which two groups of patients in sore throat,dr y mouth,fatigue,a degree of phlegm,statistically significant differenc e(P<0.05),the treatment group the severity of the symptoms is lower than the control group;Two groups of patients in terms of degree of insomnia,no statistically significant difference(P>0.05).In KPS score,we respectively before radiotherapy and radiotherapy af ter compare within the group,and there was no statistically significant difference(P>0.05);Show two groups of KPS baseline balance order,effect of Qingrejiedu and Yiqiyangyin keep in nasopharyngeal carcinoma after rad iotherapy patients physical condition has not seen significant curative e ffect.In terms of adverse reactions,two groups of adverse reactions to com pare the blood system,liver and kidney function,no statistically signifi cant differences between the two groups(P>0.05).Instructions well tolera ted in patients with Chinese medicine treatment group.ConclusionAffect of Qingrejiedu and Yiqiyangyin can reduce severe acute radiati on oropharyngeal mucosa reaction,reduce the acute radioactive skin react ion,reduce incidence of salivary gland damage of serious level and impro ve the patients quality of life after radiotherapy,experimental drug is well tolerated.