Clinical Study On The Effect Of Different Temperature Flushing Fluid On TUPKRP Intraoperative And Postoperative Bladder Bleeding

Objective: This study was conducted to explore the impact of different irrigation fluid temperature on intraoperative and postoperative bladder bleeding in patients undergoing transurethral plasmakinetic resection of the prostate(TUPKRP),in order to provide references for medical staff to select the best temperature of flushing fluid during and after the TUPKRP operation.Methods: We purposively selected 96 patients undergoing TUPKRP.All eligible patients were randomly divided into group A(n = 48)and group B(n = 48)based on the temperature of flushing fluid,The temperature of flushing fluid in group A was set equal to room temperature(20?-25?),and the temperature of flushing fluid in group B was set equal to body temperature(35?-37?).Flushing fluid samples were collected at five time periods,including intraoperative time,the first 24 h after operation,the second24 h after operation,the third 24 h after operation,and the fourth 24 h after operation.The red cell count of flushing fluid sample was repeatedly calculated three times by urine automatic analysis instrument in each time period,and the average red cell count of flushing fluid of three times wastreated as the final value in a specific time period.The age,weight,prostate volume,International Prostate Symptom Score(IPSS),duration of operation,hospital day,preoperative and postoperative axillary temperature,the number of blood clot blockage,flushing fluid volume,the number of postoperative bladder spasm in two groups were recorded accordingly.Results: 1.The postoperative volume of bladder flush fluid in group A was 33.8±4.6 L,and 20.1±8.5 L in group B(p<0.05).2.The red cell counts of flushing fluid after operation in group A and group B were both decreased with time(p<0.05).In the four 24 h periods after operation,the red blood cell counts of flushing solution in group A were all significantly higher than that in group B(P<0.05).3.The preoperative and postoperative axillary temperature had significant changed in both groups(P<0.05),and the degree of postoperative axillary temperature in group A decreased more significantly than that in group B(P<0.05).4.The bladder spasm occurred in 25 patients in group A(52.1%)and in 12 patients in group B(25%)(p<0.05).5.The basic characteristics of age,weight,prostate volume,International Prostate Symptom Score(IPSS),duration of operation,hospital day,preoperative and postoperative axillary temperature,the number of blood clot blockage,and flushing fluid volume were the same across two groups(p>0.05).Conclusion: 1.The bladder irrigation in body temperature compared to the bladder irrigation in room temperature can effectively reduce thetemperature drop of TUPKRP patients in the course of surgery.2.The bladder irrigation in body temperature can reduce the amount of hemorrhage of bladder after TUPKRP operation,and reduce the dosage of flushing fluid.3.The bladder irrigation in body temperature can reduce the incidence of bladder spasm.4.There was no significant effect on the incidence of intraoperative blood loss and the incidence of postoperative blood clot blockage in patients with TUPKRP.