Research purpose:This subject explored by water extract topical combined conventional put ascites after drug infusion cure to curative effect observation of malignant ascites, and with simple regular put ascites after drug infusion therapy, to observe the curative effect of two groups of treatment of malignant ascites and impact on patients quality of life, and the change of tumor markers and molecular biology in comparison, the influence of which discuss external governance mechanism of Chinese medicine, and provide objective basis for Chinese medicine external treatment to treat malignant ascites.Research methods:60 patients with malignant ascites were randomly divided into two groups, before and after treatment group significant difference, statistically significant, prompt 6 average can reduce, the two groups after treatment for malignant ascites all have certain curative effect; The treatment group compared with control group, the treatment group is better than the control group. Carr's score between the two groups of patients after treatment groups compared significant difference; The treatment group is better than the control group; In routine blood, liver and kidney function, tumor markers and VEGF indicators such as the treatment group was better than control group after treatment, the clinical symptoms improved and the occurrence of adverse reaction cases in treatment group is better than that of control group, showed that the treatment group compared with control group curative effect is more outstanding, and high safety.Research results:In terms of comprehensive curative effect, treatment group total effectiveness 80.0%, control group total effective rate was 56.7%; Imaging to measure liquid level biggest diameter change situation, the treatment group curative effect is more outstanding; Average 6 to compare the two groups after treatment:the treatment group is better than the control group. Cartesian score compared two groups of patients after treatment, significant difference:the treatment group is better than the control group; Two groups of patients after treatment with different degree of abdominal distention, feed increased, the increase in the number of exhaust quantity increased, the quality of life improved, through statistical analysis, the treatment group of symptoms improved more obvious; In the tumor markers and VEGF detection comparing the two groups after treatment in treatment group was better than control group; Two groups of blood, liver and kidney function and cardiac function had no significant effect, on the contrary treatment group also can to a certain extent correction of anemia and improve liver function; Incidence analysis of the occurrence of adverse reaction cases in treatment group is lower than the control group, which shows that the treatment group compared with control group curative effect is more outstanding, and high safety.Research conclusion:Apply is explored by water extract in combination with conventional put ascites after drug infusion therapy of malignant ascites is effective, on the basis of conventional western medicine treatment jointly apply is explored by water paste in alleviating clinical symptoms and signs, improve patients' quality of life and tumor markers, VEGF aspects advantage is more obvious; Compared with the control group, did not increase adverse reaction. Therefore, on the basis of conventional treatment combined apply is explored by water extract can be used as a clinical therapeutic effective means for the treatment of malignant ascites. Explored by water cream topical treatment of malignant ascites, simple and convenient operation, safe and reliable, the curative effect, worthy of further promotion. |