| Objective: Through using multi sequence high resolution 3.0T MRI,Classifying the carotid plaque,Measuring plaque burden and Analyzing its composition to investigate the correlation of carotid artery plaque typing,carotid artery plaque burden and acute cerebral infarction.Methods: Choosing sixty-five patients who had acute cerebral infarction to have MRI examination for head and bilateral carotid arteries within seven days through using Philips Intera Achieva 3.0T MRI(The skull sequences include T1 WI,T2WI,FLAIR and DWI. carotid arteries sequences include T1 WI,T2WI,3D time of fight and MP RAGE).Measuring the volume of acute cerebral infarction in DWI. According to the MRI classification criteria of the artery plaque established by Cai Jianming etc,Using the software of CASCAD to classify the plaque and analyze its composition, measure the lumen area of carotid artery and total vascular area, calculate the WA and NWI,measure the lipid core volume in carotid plaque.Using the statistical software of SPSS 20.0,measure the data by using t test,count the data by using χ2 test,The relationship between the standard index of ischemic side plaque and the core volume of Plaques in lipid with the volume of acute cerebral infarction should be used by Spearman rank correlation analysis.P<0.05 was deemed to be statistically significant.Results:(1)Within 65 cases, the image quality of 60 cases was in line with the requirements.(2)The incidence of carotid artery IV- V and VI type plaque and the lipid core in plaque, the average tube wall area,the NWI of ischemic side carotid artery wall, all items of them was higher than that of non ischemic side. The difference was statistically significant(P<0.05).(3) The NWI of carotid artery in ischemic side and the lipid core volume with the volume of acute cerebral infarction on the same side have strong positive correlations.(P<0.05).Conclusion: The carotid atherosclerotic plaque is closely related to the occurrence of acute cerebral infarction. Through the 3.0T MR, the images displayed perfectly the composition of carotid plaque, carotid artery plaque typing, the quantitative measurement of carotid artery wall burden and the volume of the interior plaque component. Consequently, providing assistance to predict the occurrence of cerebral ischemia and monitor the development of the illness. |
