Correlation Analysis Of Preeclampsia Organ Injury And Perinatal Outcomes

Objective There is few preeclampsia severity illness score for clinical activity. This article is written based on changes in preeclampsia blood biochemical indicators, ultrasound, clinical symptoms of preeclampsia to establish high-risk score in order to determine the condition properly and medical intervention process to improve maternal-infant outcomes in time.Using retrospective studies to evaluate the new severity illness score, then provide a theoretical basis for judging the extent of the patient’s condition and referral.Methods The methods are collectting the parameter values(before delivery), maternal personal general characteristics, pregnancy and delivery situation,maternal-infant perinatal outcomes and other related information retrospectively of the 205 preeclampsia cases, whose data is complete and available for analysis in the hospital maternity wards in January 2013- November 2015.Using the new score to analyse the relationship between score and maternal-infant perinatal outcomes, comparison between mild and severe preeclampsia in general situation, comparison between referral with non-referral in maternal-infant complications,and to discuss the delivery time and ways. All data were analyzed with SPSS 21.0 statistical software for analysis, using the chi-square test, Fisher exact test, t-test or ANOVA, statistically significant(p < 0.05) show differences.Results(1)There are 205 cases diagnosed as preeclampsia at admission or during hospitalization,whose data is complete and available for analysis. Only 1 case have maternal deaths, 7 cases have stillbirth, and 6 cases have perinatal death. The main causes of maternal death are respiratory and circulatory failure, the directive cause of perinatal death was severe asphyxia.(2)The lower the high-risk score, the less affected organs. Because of the existence of individual differences which makes different organ involvement. Score ≥5 points, one organ involvement incidence increased(p=0.024); score ≥11 points, two organs involvement incidence increased(p=0.038); score ≥17 points, three organs involvement incidence increased(p=0.002); score ≥21 points, the incidence of four organs involvement increased(p=0.019).(3)Higher score, higher severe perinatal infant asphyxia and stillbirth rate. The main cause of perinatal death of serious mother complications is placental abruption.(4)The scores increased, gestational age is terminated in advanced. 23 cases of vaginal delivery, and most of them are multipara, 174 cases of cesarean section. With the score increasing, the proportion of cesarean section substantially tend to increasing.(5)Other hospital referrals number is 92, preeclampsia scores, number of organ damage and complication rates were higher than the non-referral patients.Conclusions(1)The new evaluation system can assess general condition who with preeclampsia, and has certain guiding significance for clinical diagnosis and treatment.(2)The higher scores is made at admission time the more organs involvement, the more severe the disease is, and the greater chances of fetal and maternal complications have.