The Clinical Trials On Stable Angina Pectoris (Deficiency Of Both Qi And Yin) Treated With Tongmaiyangxin Pill

Objective:By observing Tongmaiyangxin pill intervention clinical efficacy and safety of stable angina patients (deficiency of both Qi and yin), to guide clinical more reasonable and safe medication.Methods:Select the 50-75-year-old Qi and Yin Deficiency symptoms of stable angina patients in this study, a randomized, double-blind, placebo-controlled method, selected in line with the conditions of the patients were enrolled, a total of 20 patients were randomly divided into two groups 10 cases,10 cases in the control group. Experimental group received Tongmaiyangxin pill 40/times,2 times/day orally; control group received Tongmaiyangxin pill simulant 40/times,2 times/day oral medication time is 12 weeks. Observed, compared to patients before and after Tongmaiyangxin pill Seattle Angina scale score as well as liver and kidney function and other safety indicators, evaluation of the drug in patients with stable angina pectoris (deficiency of both Qi and yin) the efficacy of and security.Results:1:Results after treatment trial group limited physical activity levels, stabilization state of angina, angina pectoris attack situation, treatment satisfaction, degree of disease cognition to improve before the treatment (P< 0.05). The placebo group after treatment before stabilization state of angina and treatment satisfaction and disease cognition improved (P < 0.05). On the comparison between groups, compared with control group, experimental group limited in physical activity level, the state of stable angina, angina is three points on the difference was statistically significant (P< 0.05), and the rest the difference has no statistical significance (P> 0.05).2:Comparison of the two groups before and after treatment within the safety index group, the difference was not statistically significant (P> 0.05), and no drug-related safety test abnormalities.Conclusion:1. Tongmaiyangxin pill can improve stable angina (deficiency of both Qi and yin) after treatment in patients with limited physical activity levels, heart colic steady state, angina attack, cognitive degree of satisfaction and disease treatment.2. Tongmaiyangxin pill have no wrong effects on liver and kidney function.