Intervention Of Membranous Nephropathy Syndrome Distribution Characteristics And Gujing Yiqi Party

Objective:To analyze idiopathic membranous nephropathy (idiopathic membranous nephropathy, IMN) different course syndromes distribution characteristics; observe Gujing Qi Treatment efficacy in patients with IMN and 24h urine protein, serum albumin, serum total protein influences.Method:Studyl:Eligible collected 100 patients with IMN, in the form of a questionnaire, collecting information on the patient's condition, according to age of onset patients were divided into 4 groups, namely group A (within 1 year), group B (1-3 in group), group C (3-5 years group), D group (over 5 years). Using statistical tools were four groups of patients the disease were analyzed; application of TCM method to analyze each group of syndromes characteristics. Study2:The 30 cases of patients with IMN TCM is qi deficiency of spleen and kidney, on the basis of necessary treatment, with Qi Gujing 3 months of treatment. Respectively, before treatment, one month, two months, three months to detect patients with 24h urinary protein, serum albumin,serum total protein and other laboratory parameters and changes in symptom scores, and statistical analysis.Results:1.100 patients surveyed, this deficiency Syndrome Types of TCM in the A, B, C, D four groups the percentage was as follows:Spleen Deficiency 52.6%,39.1%,25.0%,10.5%; kidney deficiency 10.5%,13.0%, 15.0%,21.1%; spleen and kidney yang 15.8%,13.0%,15.0%,15.8%; liver-kidney 13.2%,17.4%,20.0%,26.3%; Qiyin deficiency 7.9%,17.4%, 25.0%,26.3%.2.100 patients surveyed, standard empirical Syndrome Types of TCM in the A, B, C, D four groups were percentage:34.2% rheumatic syndrome, 21.7%,15.0%,5.2%; damp-heat syndrome 26.3%,26.1%,10.0%,5.2%; stasis syndrome 23.7%,30.4%,35.0%,42.1%; 15.8% dampness syndrome, 21.7%,40.0%,47.4%.3. Total Gujing Qi Treatment of patients in the observation period IMN effective rate of 73.3%. Course of a month, IMN 24h urinary protein in patients with lower than before treatment (P<0.05), serum albumin, total plasma protein levels higher than before treatment (P<0.05); course of 2 months, the patient 24h urine protein low in the course of one month (P <0.05), serum albumin, total plasma protein levels higher than a month of treatment (P<0.05); treatment for 3 months,24h urinary protein in patients with less than 2 months of treatment (P< 0.05), serum albumin, serum total protein levels above 2 months of treatment (P<0.05). Treatment for 3 months, compared with treatment, the symptom ccore reduced (P<0.05).Conclusions:1. IMN deficiency in this:the early onset type IMN TCM spleen and kidney Deficiency mainly; with disease progression and hormones, immunosuppressive therapy, liver-kidney, lung and kidney Qi and Yin Deficiency type and type of patient gradually increased; spleen and kidney yang in the distribution of no significant changes.2. IMN standard empirical in:In the early stages of rheumatoid syndrome, damp syndrome based; with disease progression, and blood stasis as the main syndromes; duration of more than five years in patients with dampness syndrome began to appear, and gradually increase with the duration increase.3. Qi Gujing treatment in patients with IMN observation period, the patient can reduce urinary protein excretion 24h enhance plasma albumin, total plasma protein levels, and relieve symptoms have a certain effect.