Study On Prescription Regularity Of Compound Chinese Medicine In Treatment Of Viral Myocarditis Based On Clinical Evidence

Objective: To investigate the effect of compound traditional Chinese medicine in treating viral myocarditis drug laws, key compatibility and core treatment, for the clinical treatment of the disease provide theoretical reference. Methods:(1) search of CNKI, VIP, Wanfang Data and database of the Chinese herbs in the treatment of viral myocarditis clinical research literature, selected to meet the requirements of clinical controlled trials and to research into the effectiveness of evaluation;(2) from the effective prescriptions for screening evaluation system, using traditional Chinese Medicine Inheritance support system(v2.5) was used to analyze the data;(3) to summarize the treatment of viral myocarditis prescription regularity and core treatment. Results:(1) screened met the inclusion criteria of 343 clinical studies, involving the treatment of adult viral myocarditis TCM compound 285, compound Chinese medicine treatment of viral myocarditis in children of 74;(2) Meta- analysis showed that 3 of the selected prescription efficiency compared with no statistical significance in clinical treatment, suggesting invalid the remaining 340 studies, 359 prescriptions for viral myocarditis;(3) analyzing the data of effective drugs in the prescription, prescription in adults(support 50% and 0.85 confidence level) from 5 kinds of core group, children in the prescription(support 35% and 0.8 confidence level) from 2 taste the core group;(4) respectively for the treatment of adult and pediatric viral myocarditis in the 180 and 104 drugs for functional classification and summary of resistance;(5) analysis and treatment of adult using complex system entropy clustering Children with viral myocarditis were treated with 8 and 6 alternative prescriptions. Conclusion:(1) Chinese herbal compound in the treatment of viral myocarditis has obvious curative effect, small toxic side effect and high stability;(2) Qi-Reinforcing Drugs, blood stasis, tonifying qi and Yin tonifying drug detoxification, heat clearing drug, heat clearing drug, astringent drug, diaphoretic, blood medicine 9 drugs as the main function of the treatment of adult viral myocarditis(82.14%); the category of drugs, blood stasis, tonifying qi and Yin tonifying drug detoxification, astringent drug, heat clearing drug, blood medicine, heat clearing drug and other 8 drugs as the main function of the treatment of infantile viral myocarditis(about 80% categories of drugs);(3) Huangqi-Danshen Radix- Ophiopogonis Schisandra- Zhigancao association between treatment of adult viral myocarditis common core medicine group was the highest, salvia, Jiang Banxia, Shichangpu as the core drugs associated with the highest new party candidate; Salvia miltiorrhiza and Fructus schisandrae chinensis Association of the highest in the treatment of infantile virus myocarditis commonly used core medicine group, snakegourd fruit, cassia twig the highest relevance of alternative new drugs on the core;(4) clinical by supplementing qi and nourishing Yin, heat clearing and detoxifying, promoting blood circulation to remove blood stasis, Ning Anshen is the main treatment, according to the drug and permit the appropriate compatibility nourishing blood and eliminating dampness, astringent, solution table, soothe the nerves, dampness, phlegm, resuscitation, etc., can be composed of rousing, specimen and cure effective clinical compound.