Meta Analysis On The Treatment Of Hypertension By Acupuncture And Moxibustion Therapy Based On Randomized Controlled Trials

Objective: Collected the database start year of play at home and abroad all published acupuncture therapy in the treatment of hypertension in both Chinese and English of randomized control study, application system evaluation method evaluation the efficacy and safety. And based on the existing literature, evidence evaluation of acupuncture and moxibustion therapy in the treatment of hypertension level, provide evidence for writing guide.Materials and methods: According to the requirements of the evaluation system, take electronic retrieval and manual retrieval combining a comprehensive search in both English and Chinese database. Inclusion criteria literature screening and data extraction, and then to research into the literature quality assessment and data synthesis, generated by two independent researchers from random allocation scheme, hiding scheme, blind method, data integrity and selective reporting to be included in the quality literature evaluation. Were used to lower blood pressure numerical, antihypertensive efficiency and syndrome improvement as the antihypertensive efficacy evaluation of the primary outcome measures of acupuncture therapy. The software provided by the Cochrane Collaboration of statistical credit Analysis.Results: A total of detection literature 4092, which 277 duplicate documents, by reading the title and abstract screening, excluding 3558, by reading the full text, excluding the non randomized controlled study of 48, 48 semi random study excluded articles, because the data is not excluded 57. Due to the elimination of the primary outcome measures 39, repeat: 14. Included in the final 15 clinical trials. After data extraction, analysis and descriptive analysis. Results showed that acupuncture and moxibustion therapy and two acupuncture therapy combined with compared with western medicine inthe blood pressure value, dynamic blood pressure, the effectiveness of the buck, syndrome curative effect with efficiency and TCM Syndrome integral Surface have significant difference; compared to the blood pressure values in the therapy of acupuncture and moxibustion combined with western medicine and the single application of Western medicine, syndrome curative effect, TCM syndrome score have significant difference, but acupuncture therapy combined with western medicine in step-down efficiency no statistical difference.Conclusion: This study showed that single acupuncture therapy and acupuncture therapy combined with the blood pressure value of ambulatory blood pressure, Buck efficiency, syndrome curative effect of efficiency and TCM syndrome score advantage; acupuncture therapy combined with western medicine on the blood pressure value, syndrome curative effect, TCM syndrome score showed a certain advantage, but a kind of acupuncture therapy combined with western medicine in the step-down efficiency no advantage in the treatment period has not been found to have obvious adverse reactions. The acupuncture therapy in the treatment of hypertension clinical trial methodology quality is generally low, and not the implementation of high levels of random distribution, the lack of reasonable control measures(placebo effect is not clear). Therefore, to carry out high Quality, large sample, multi center, randomized, double blind controlled trials are needed to further confirm the stability and accuracy of the above results.