The Clinical Research For The Treatment Of Jia-wei-bu-yang-huan-wu Joint Tripterygium Wilfordii Glycosides Tablets Toidiopathic Membranous Nephropathy

Research purposes: based on the treatment of western medicine, give bu yang huan wu tang also joint tripterygium wilfordii on the clinical effect of the treatment of idiopathic membranous the differences in the clinical curative effect, in order to investigate tonifying Yang also five decoction on the effectiveness of the treatment of membranous nephropathy to improve the clinical symptoms, and to combine traditional Chinese and western medicine in the treatment of membranous nephropathy development provide certain enlightenment.Research methods: the study samples of total revenue, 30 cases were the pathological diagnosis of idiopathic membranous nephropathy, TCM syndrome classification for qi and blood stasis, with 30 samples by blind method will randomly divided into two groups, each group for 15 samples. Control group used in western medicine and tripterygium wilfordii glycosides tablets, the experimental group and fill with flavored Yang also five soup with card to add and subtract, the observation time is 90 days, all of the patients in the experiment were determined before and after the plasma albumin, 24 h urinary protein, serum creatinine, blood urea nitrogen and quantitative biochemical indicators, and analyze the evaluation of contrast, verify the curative effect.Results: in the flavored Yang also more than five soup combined tripterygium wilfordii glycosides tablets on the treatment of idiopathic membranous nephropathy and use tripterygium wilfordii glycosides tablets with the same effect. Fill flavored Yang also more than five soup combined tripterygium wilfordii glycosides tablets in the aspect of improving syndromes than use tripterygium wilfordii glycosides has advantages. Fill flavored Yang also more than five soup combined tripterygium wilfordii glycosides and use tripterygium wilfordii glycosides more pills on reducing urinary protein was no significant difference. Fill flavored Yang also more than five soup combined tripterygium wilfordii glycosides and use tripterygium wilfordii glycosides more pills for high plasma albumin has no obvious difference. Renal protection in western medicine and tripterygium wilfordii five soup combined with western medicine plus fill Yang also no difference between the tripterygium wilfordii scheme. During the whole observation, there were 1 case of drug side effects, and 1 case from the control group, control group considered caused by tripterygium wilfordii glycosides more serious adverse reactions. Consider the traditional Chinese medicine can play a role of must protect liver to protect liver, can reduce the side effects of tripterygium wilfordii.Conclusion: on the basis of the western medicine treatment on the basis of five soup flavored filling Yang also joint tripterygium wilfordii can significantly improve idiopathic membranous nephropathy and qi stagnation and blood stasis type can effectively improve the patient's symptoms such as swelling, drowsiness, fatigue, but compared with the control group in improving plasma albumin, urine protein has no obvious advantages, but it can reduce side effects, can improve the use of the possible adverse health effects of tripterygium wilfordii glycosides tablets more fill the flavored Yang also more than five soup combined tripterygium wilfordii glycosides tablets in the treatment of IMN has high clinical value, worthy of further application research.