Preparation Of Novel Biomedical Polymers And Their Biocompatibility Evaluations

Biomaterial refers to devices that are medically applied into or onto human body. Their application involves various areas including medicine, surgery and rehabilitation. As is known to all, biomaterial is playing an essential role in contemporary medicine. They are used to ease pains, save lives and improve patients'life quality. With the development of medicine and civilization, there is an increasing demand and expectation for biomedical. With the growth of medical materials, we should also pay attention on their criteria—biocompatibility, which is more vital to human beings. It is the most basic requirement for biomedical materials and the most important distinction between biomedical materials and other materials. Only if biomedical polymer has a high biocompatibility can it be applied and be effective to human body. Borneol, a traditional Chinese medicine, is of satisfying clinical practice. This paper describes its new application to create new functional biomedical materials, reviews its biocompatibility. The key results are as follows:1. The polyborneolacrylates (PBAs) has good cellular compatibility and chemical stability with no cytotoxicity, which meets the high national standard.2. Both L-PBA and D-PBA have good biocompatibilitiy. Chiral effect displays on both cell adhesion and protain adsorption.3. The PBAs have the advantage of anti-bacterial adhesion. It is promising for use as biomedical materials.4. By multicomponent polymerization reaction, the designed borneol-based polymer (PSB) is proved to be a material with good stability, no cell toxicity, and good cell compatibility.5. Through combined with cellulose, the borneol-grafted cellulose (BGC) also exhibit good biocompatibility and chemical stability. Especially it can prevent the growth of fungi, which enables BGC to have an exciting value and future prospects.